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Development of a gel for liver cell culture on microchips
Hydrogels could be used to build organs on chips to test potential medications, with the aim that they could potentially replace animal studies...
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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Efficacy of breast cancer therapy measured using PET imaging
Researchers have developed a method using PET imaging along with 18F-fluorofuranylnorprogesterone to analyse the efficacy of breast cancer treatments...
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Diagnostic technique reveals biomarker differentiating bladder cancer from inflammation
A biomarker that can differentiate between chronic cystitis (inflammation of the bladder) and a non-muscle invasive-type blood cancer could aid diagnosis...
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Genomic approach to studying widespread malaria
Researchers have suggested that the most widespread human malaria parasite could be studied and possibly treated using genomics...
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Protecting vision after optic nerve trauma using arginase 2
Arginase 2 could be used as a drug target target to protect vision after optic nerve trauma, as removal of this enzyme decreases retinal neuron death...
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Functional transplantable B-cells generated from mice
Stem cells generated from mice have shown to be functional when transplanted, leading to the possibility of future therapies...
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Protection against Mayaro virus using engineered DNA vaccine
An engineered DNA vaccine that induces a robust and specific immune response against the disease, also provides complete protection...
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Hit-to-lead discovery at a nonprofit research institute
Small molecule drug discovery has long been the domain of pharmaceutical companies, and that’s not likely to change anytime soon. But there’s a cadre of universities and nonprofit research institutes that have embraced drug development at its earliest stages, in some cases identifying and optimising compounds that target possible disease-driving…
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The role of immune cells in metastasis
Specific immune cells, such as neutrophils, have been found to aid the progression of cancers, promoting metastasis in tumours...
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Virtual drug discovery tackles unknown universe of drugs
An online compound library consisting of the structure of over a billion molecules could be the future of drug discovery...
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Treatment could prevents and treat Chlamydia
The development of a treatment that prevents and treats Chlamydia uses nanotechnology, and could change the way the disease is treated...
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Key function of specialised cells in peripheral nerve repair
The interaction between macrophages and Schwann cells could be vital in maintaining the repair process, without which could impair nerve function...
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Mucus could be key to treating colon and airway diseases
The action of proteins that control mucus production could suggest clues to treating colon and airway conditions such as asthma or Crohn's disease...
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The path of metallodrugs in breast cancer cells
The path a metallodrug uses to target and kill cancer cells could be used to design drugs to target triple-negative breast cancer...
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Clusterin linked to both cardiac and metabolic diseases
The protein clusterin has been linked to different cardiometabolic syndrome risks, with researchers asking whether it could be a therapeutic target...
