news
Novel antibiotics can be found on common weeds
The team studied chemical compositions in detail and from one strain of bacteria several antibiotically active chemical substances were discovered...
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
news
New ligand binding site identified through computer simulations
Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...
news
CMPK2 inhibitor could lesson symptoms of common illnesses
CMPK2 inhibitors may reduce inflammation, pain and tissue damage in arthritis and gout and in Alzheimer’s may slow loss of cognitive function...
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New drug for ALS ready for clinical trials
Previous studies have suggested that a gene therapy drug may be used to treat ALS...
news
BCX7353 shows hope for hereditary angioedema
A new drug has been developed to help prevent attacks of hereditary angioedema and at the same offer patients a convenient administration...
news
Promising drug targets for t-cell lymphoblastic leukaemia
Silencing the gene behind the production of HSP90, a target in the HSF1 pathway, effectively kills leukaemia cells, without affecting healthy cells...
article
Adapting drug discovery to Artificial Intelligence
Drug discovery has always been challenging; today, more so than ever. While there has been success in addressing many diseases, others remain intractable...
article
Improving the translation of disease biology though phenomics
How times change. Up to 15 years ago, you would be hard-pressed to find a drug discovery conference with a track dedicated to phenotypic approaches. The underpinning science was called high-content imaging or analysis, being mainly confined to academic drug discovery labs and a handful of pioneers in industry. but…
whitepaper
Application Note: ATPlite assay performance in human primary cells
ATPliteTM and ATPlite 1step are robust, rapid, high-throughput luminescence assays used to assess a compound’s druggability.
news
IgE protein may protect against skin cancer
The components of the immune system that trigger allergic reactions may also help protect the skin against cancer, suggest new findings...
whitepaper
Whitepaper: A guide to achieving better insight with accurate data
In today’s modern world, data is everywhere. This eBook will guide you through the steps of how to achieve more with accurate data.
whitepaper
Tech note: Detection of immune checkpoint markers in peripheral blood mononuclear cell lysates with AlphaLISA
Quickly and easily quantitate immune checkpoint markers using a fraction of the sample volume required by traditional ELISAs...
video
Video: PHERAstar FSX Customer testimonial
In this video, Becky Allsopp from Sygnature Discovery talks about Drug Discovery Research and how she uses the Microplate Reader PHERAstar FSX for their research.
whitepaper
Tech note: Fast, simple, homogeneous assays for characterisation of Fc receptor binding using AlphaLISA
AlphaLISA® provides a robust assay that facilitates the design and development of antibody therapeutics.
news
Malaria vaccine targets PMIF
A new malaria vaccine targets the protein PMIF, which is crucial in the life cycle of malaria parasites...