whitepaper
Whitepaper: Opportunities in preclinical development
This whitepaper explains how you can find ways to optimise the holistic preclinical development process...
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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Genomics in drug development and safety testing; from target identification to genomic toxicology
In the annual report of the Chief Medical Officer, 1 Dame Sally Davies has declared that we are part of ‘generation genome’ – the era in which we reap the rewards of our advances in genomic technologies and improvements in our understanding of the whole genome in human health.
news
Progress toward improved Wilson’s disease drug
Researchers have conducted promising preclinical experiments on a compound that could be used to treat Wilson's disease...
news
Experimental drug combined with radiation extends the survival of GBM
A new study has shown that an experimental drug known as AZ32 significantly extends the survival of glioblastoma multiforme, the most common and deadly form of brain cancer...
news
Mini-ecosystems developed to test a molecules therapeutic effect
Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'mini-ecosystems to quickly see if a molecule can function as a potential therapeutic...
product
Mouse IgG type and Titer Kit
15 June 2018 | By IntelliCyt
The Intellicyt Mouse IgG Type and Titer Kit is a high throughput, multiplexed assay kit that enables analyses of isotype, titer and cell health in a single assay...
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Streamlining drug discovery assays for cancer and cardiovascular disease
For lead optimisation, target-based assays are still the most affordable means of rapidly performing fast iterations and remain core to screening. However, the desire for biological relevance is driving ongoing growth in cell-based assays.
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Expert view: Rising growth of the global high‑content screening software and services market
The global high-content screening (HCS) software and services market accounted for over $500 million in 2017 and is expected to reach approximately $1.4 billion by 2026, increasing at a compound annual growth rate of more than 11%, says Jeff McMillan, Senior Product Manager Imaging, Molecular Devices.
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Transforming translational research: CANscriptTM – a better predictive model for oncology
This webinar focused on a recent study evaluating a cohort of head and neck squamous cell carcinoma (HNSCC) patient tumours treated with anti-PD1 using CANscript™.
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Automated assessment of liver and cardiac toxicities in lead optimisation
This webinar, supported by Tecan, focused on the automated assessment of liver and cardiac toxicities in lead optimisation, using biochemical and human iPS cell assays.
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Expert view: Overcoming the problems of working with human primary hepatocytes
Human primary hepatocytes (hpheps) are the gold standard for in vitro evaluation of drug metabolism, drug-drug interactions, and metabolic disease research. However, hpheps don’t survive in standard 2D culture for very long – no longer than two or three days.
whitepaper
Application note: Cellartis® Power™ Primary HEP Medium – extend functionality of your primary hepatocytes to 4 weeks
Human primary hepatocytes (hphep cells) are the gold standard for in vitro evaluation of drug metabolism, drug-drug interactions, safety assessment of drug candidates, and disease modeling.
news
Scientists create ‘genetic atlas’ of proteins in human blood
Researchers have created the first detailed genetic map of human proteins...
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Expert view: Biological therapeutics are becoming more popular, here are the reasons
For most people, traditional High-Throughput Screening (HTS) represents large automation rigs and large libraries of small molecules screened against drug targets, however, the development of biological therapeutics has been gaining considerable pace for many reasons.
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Expert view: How high-content platforms keep pace with the changing face of cell-based drug screening
For the next generation of cell biologists, 3D cell culture and analysis has opened doors to taking applied research one step further.