New small molecule blocks immune response signalling pathway
A new small molecule has great promise for the treatment of autoimmune diseases by inhibiting the proinflammatory signalling pathway.
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In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
A new small molecule has great promise for the treatment of autoimmune diseases by inhibiting the proinflammatory signalling pathway.
An epitope on CD95 receptor causes tumour cells to self-destruct and may prolong benefits of CAR T-cell therapy for solid tumours.
New research presented at the European Academy of Dermatology and Venereology (EADV) Congress 2023 in Berlin, Germany, has highlighted a previously underestimated aspect of acne's impact on individuals: its profound influence on social perception.
The sensation of itch is something everyone has experienced at some point in their lives. It's a natural response to various irritants, from insect bites to dry skin. But what happens when the urge to itch becomes relentless, causing discomfort and, in some cases, serious health problems?
Researchers have achieved profound insights into the inner workings of a prevalent environmental bacterium.
Sino Biological are pleased to announce the formal opening of its new center for Bioprocessing (C4B) in Houston, Texas USA at Levit Green, adjacent to the world-renowned Texas Medical Center.
Dr Nicolas Camper at CDMO Abzena and colleagues offer insight into the landscape of antibody-drug conjugates and how the therapy is evolving.
Artificial intelligence (AI) and machine learning (ML) have been gaining significant attention lately, primarily in discussions about their responsible utilisation. However, these technologies possess a wide spectrum of practical applications, ranging from predicting natural disasters to addressing social disparities. Now, AI is making its mark in the field of cancer…
29 September 2023 | By Analytik Jena
Watch this webinar to learn how PROTACs are revolutionising drug discovery, and the critical role protein purification plays in the production of therapeutic proteins.
This September edition of our Women in Stem series spotlights Dr Emily Leproust, CEO of Twist Bioscience. Dr Leproust began her STEM journey from a background in chemistry, eventually leading her to the forefront of DNA synthesis technology. She co-founded Twist Bioscience in 2013, now a thriving company reporting substantial…
Researchers at the University of Queensland have discovered a promising drug target capable of addressing drug resistance and preventing tumour regrowth in cancer patients.
Human derived induced pluripotent stem cells (hiPSCs) have revolutionised research and are increasingly used for toxicology screening and disease modelling. Early detection of neurotoxicity induced by potential new therapies is a major challenge, and hiPSC-neuronal cells may provide a solution. These cells demonstrate considerable promise for uncovering drug-induced perturbations to…
Organoids, lab-grown 3D structures that mimic human organs, are redefining preclinical research through bypassing the ethical and practical limitations of animal models. Technological advancements in organoid research, including automation and improved analytical tools, promise to unlock new possibilities by streamlining the application of these 3D structures to enhance drug development…
This article discusses the need for adulticidal drugs to treat Onchocerca volvulus infections, a parasite causing onchocerciasis (river blindness), as the current treatment with ivermectin and surgery presents challenges for affected communities. It highlights research findings on the potential of analgesic medicines to target adult worms and emphasises the importance…
Rob Scoffin and Matthew Habgood from solutions provider Cresset look to the future of drug discovery and the roles that artificial intelligence and machine learning could play.