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Halting the spread of brain cancer
Mouse models used to show how convection enhanced delivery caused glioma cells to invade the rest of the brain could help to prevent this spread in future...
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Breast cancer recruits cells from bone marrow to boost growth
A study has shown that breast cancer uses stromal cells originally formed in bone marrow to boost their growth and metastasis of the cancer...
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Study reveals 35 genes linked to chronic kidney disease
A study conducted by researchers at The University of Manchester and Manchester Children's Hospital has revealed 35 genes linked to chronic kidney disease...
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Nanopore detection of single flu viruses to control influenza outbreaks
Osaka University researchers have developed a method using single-particle nanopore sensors and AI to detect single influenza virions...
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War On Cancer 2018: targeted therapies in oncology
War On Cancer 2018 discussed how cancer treatments have evolved over the last few decades, and looked at the future of cancer therapies...
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Majority of HIV persistence during ART due to infected cell proliferation
Study confirms biological mechanism responsible for latent HIV reservoirs; suggests strategies for a functional HIV cure...
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Vaccinia virus hijacks cellular movements to spread
To spread throughout the body, the vaccinia virus mimics the infected cells' own proteins enabling the cell to move around and spread...
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RIP1 kinase as a therapeutic target for pancreatic cancer
RIP1 has been shown to suppress the action of macrophages against the immune system and could be a potential therapeutic target for pancreatic cancer...
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Mouse model for diabetic kidney disease suggests role for immune and inflammatory pathways
Scientists have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy...
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Drug repurposing using off patent drugs as antifungals
Researchers have identified that Alexidine dihydrochloride can be used as a broad spectrum antifungal, and can also kill biofilms formed by these fungi...
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Gene responsible for hair loss discovered
The gene responsible for hair loss caused by the hypotrichosis simplex has been discovered by researchers at the University of Bonn...
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Scientists pinpoint mechanism by which mutant p53 protein promotes cancer
Scientists in Australia have discovered how the most important gene in preventing cancer, TP53, is hampered in its tumour-fighting efforts by mutant p53 proteins.
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Making old antibiotics work better using r8
A team of researchers have developed a way that could enhance the effect of current antibiotics, using a small molecular attachment called r8...
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Parasitic worm study predicts potential drug targets and drugs
The largest ever parasitic worm study has revealed nearly 1 million new genes, and has identified potential drug targets and drugs...
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Potential of gene therapy for neurological disorders
Gene therapy could be effective in numerous neurological conditions and could transform the lives of patients with these incurable diseases...
