NGLY1 protein identified as potential target for melanoma treatment
Scientists in the United States have inadvertently uncovered a promising treatment for melanoma that targets the NGLY1 gene.
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A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
Scientists in the United States have inadvertently uncovered a promising treatment for melanoma that targets the NGLY1 gene.
The mechanisms and actions of heat-resistant enzymes are being investigated to aid better, more cost-effective drug design...
Charles River Laboratories International, Inc. (NYSE: CRL) announced that its team of neuroscience drug discovery experts will present 26 scientific posters, both independently and collaboratively with clients, at Neuroscience 2018, the 48th annual meeting of the Society for Neuroscience (SfN)...
The Tn antigen appears in around 90 percent of cancers, and its structure is greatly affected by the addition of water molecules...
Scientists in the U.S. have published their findings about the behaviour of proteins in mouse eggs, projecting possible impacts on infertility and cancer treatment.
Cryo-EM was used to image the antibodies attaching to the circumsporozoite protein, which is the most abundant protein on the surface of malaria...
Researchers at MIT have identified a way to stimulate a particular stem cell in order the hasten the regeneration of red blood cells...
A cell structure identified has given an insight into how cells attach to their surroundings, and could be used to discover potential actions of new drugs...
Single molecule fluorosequencing could revolutionise the way researchers analyse disease, with the method enabling the investigation of single cells...
Study of genomic data from breast cancers of Nigerian women, compared with American women, highlights significant differences that may help targeted treatment for the epidemic across Sub-Saharan Africa.
Sensory hair cells could be regenerated using a therapy developed from the action of the cells in animals such as birds, fish and frogs...
Targeting the fibrin protein could ensure that fibrin leaking through the blood-brain barrier does not cause inflammation or disease in the brain...
Researchers have pinpointed a single molecule - microRNA-31 (miR-31) - the levels of which predict whether a patient has subtype 1 or subtype 2 of Crohn's disease...
Researchers have identified that the RNA molecule nc886 begins a series of events that leads to the destruction of viruses...
A bridge-like structure in oestrogen has been identified by researchers at Case Western Reserve University School of Medicine as a potential drug target...