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A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
Over the past decade, pharmaceutical industries have contributed enormously to the discovery of new innovative drugs that have saved countless human lives. Discovering new drugs is a complex team sport that requires an intellectual collaboration across many sectors. These advancements provide powerful tools that arm scientists in the quest for…
Breakthrough research has uncovered an unexpected mechanism that underlies cardiomyopathy in DMD...
Researchers have identified the dectin-1 pathway as being a potential target for the treatment of pain associated with candidiasis...
Scientists have discovered the chemical compound AT-121, which could soon lead to a painkiller stronger than morphine, but without the side effects...
Researchers have described the discovery of a molecular link between ageing and a major genetic cause of both ALS and FTD...
An experimental drug is reported to have potential to treat Epstein-Barr virus related lymphomas by counteracting the cancer-promoting mechanisms of LMP2A...
Researchers have discovered that a very common protein in the brain has an additional significant role in addiction relapse...
Researchers have finally been able to mimic IPF in mouse models - a debilitating disease, with no proper treatment and no cure...
Mouse models showed promise when an anticancer drug was used to treat liver failure, resulting in liver regeneration and preventing liver related death...
"As an experimental chemical, further rigorous testing and refinement of KHS101 is required before trials in people can begin.”
The research team identified that the more the DNA was damaged, the more RUNX proteins bound to DNA repair intermediaries...
Computational methods accelerates and automates the process of optimisation of candidate molecules before performing preclinical trials...
Dr Bivona and his team showed that the growth of multiple cancers slowed by suppressing the signalling pathway using an experimental compound...
New research shows that immune cells developed from early exposure to bacteria contribute to vision loss in glaucoma patients...
PARP inhibitors show promise in preventing toxic accumulations of brain disease proteins in Penn research study...
