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Drug Targets

A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.

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Advancing the understanding of placenta accreta spectrum disorder

1 February 2024 | By Drug Target Review

A new study has identified targets to refine diagnostic tests, track disease progression, and discover more effective therapies.

whitepaper

Application Note: Understanding The Multiplex Imaging Landscape

1 February 2024 | By Leica Microsystems

Learn about the different types of multiplexed imaging available, as well as their applications, benefits and disadvantages.

whitepaper

Application note: In situ identification of cancer stem cell niches (HCC)

1 February 2024 | By Leica Microsystems

This app note explores a groundbreaking multiplex immunodetection approach to identify cancer stem cell niches within hepatocellular carcinoma (HCC).

Human heart with heart vessles inside human body and ECG, 3D illustration

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Replacing the PKP2 gene prolongs survival in ARVC patients

31 January 2024 | By Drug Target Review

The new study suggests that this gene therapy method may combat ARVC in both early and more advanced stages of the condition.

whitepaper

Consistent, functional lower motor neurons from iPSCs

26 January 2024 | By bit.bio

How pure consistent and functional lower motor neurons can be precision reprogrammed from iPSCs for motor neuron disease research and drug discovery.

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Knockdown of FAM3C inhibits breast cancer tumour growth

22 January 2024 | By Drug Target Review

Inhibition of FAM3C expression in cancer-associated adipocytes during early tumour development holds promise as a novel treatment approach.

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Blocking the IL-6 receptor to protect tissues from CRS

18 January 2024 | By Drug Target Review

The new study’s findings suggest that CRS can be treated with an IL-6 receptor antibody that has a short half-life.

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Finding the fundamental pathway in ALD pathogenesis

17 January 2024 | By Drug Target Review

Liver-specific knockdown of TRPC3 enhanced alcohol's inhibitory effect on AMPK through a mechanism of Ca2+-dependent CaMKK2 activation.

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How breast cancer cells take advantage of the extracellular matrix

17 January 2024 | By Drug Target Review

Researchers discover a key metabolic process that cancer cells use to grow in a nutrient deprived environment, which could be a new target.

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RBM5: potential drug target for acute myeloid leukaemia

15 January 2024 | By Drug Target Review

RBM5 removal from cells meant that HOXA9 mRNA levels were greatly reduced, which could lead to therapies targeting HOXA9-driven leukaemia.

article

How AI is accelerating the future of precision medicine

12 January 2024 | By Ellen Capon (Drug Target Review)

Dr Ketan Patel, Clarivate, shares his insights about the use of Real-World Data and genomic biomarker data and discusses how researchers can use these to better detect and diagnose diseases.

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eBook: Modern Microscopy in Cancer Research

10 January 2024 | By Leica Microsystems

Explore the history and trends of microscopy in cancer research and discover the latest cancer imaging solutions and techniques in this eBook.

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Article: Tips and Tricks for Leveraging Advanced Flow Cytometry

9 January 2024 | By Sartorius iQue®

Tips and tricks for fully leveraging Advanced Flow Cytometry.

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Application note: Direct and Competitive Live Cell Antibody Binding

9 January 2024 | By Sartorius

Utilizing Advanced High-Throughput Flow Cytometry to Quantify Direct and Competitive Live Cell Antibody Binding

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Controlling MYC’s hyperactivity with a peptide compound

8 January 2024 | By Drug Target Review

A novel peptide can suppress MYC by binding directly to it with sub-micro-molar affinity, advancing cancer drug development.

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Drug Targets