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ebook: Quantitative Assays to Measure Ab Binding to Fc Receptors
This ebook summarizes the basics of Fc receptor function and discusses biochemical and cell-based assays that enable antibody optimization projects.
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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New insight into BRCA2 gene mutations and cancer risk
A recent study from researchers at the University of California examines the BRCA2 gene, which plays a crucial role in repairing damaged DNA, and possible links with increased risk of breast and ovarian cancer.
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Challenges and promises of personalised precision medicine
Drug Target Review’s Taylor Mixides exclusively interviews Neil Thomas, Partner and Head of Healthcare and Life Sciences for EMEA at Infosys Consulting, on personalised precision medicine, its advances, challenges and the future.
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Revolutionary nanoparticles enable gene-editing in lungs
This article outlines the development of a new type of nanoparticle that can perform gene-editing in the lungs. Scientists from MIT and the University of Massachusetts Medical School have collaborated to create this Ribonucleic acid (RNA) delivery particles, which have the potential to revolutionise the treatment of lung diseases such…
news
Recombining drugs helps restore gene’s ability to signal for death of leukaemia cells
US researchers find combination of chloroquine and venetoclax promotes cancer cell death in mouse models with acute myeloid leukaemia (AML).
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Cannabinoids used in worms can help regulate various body systems
US study suggest worms could be a good research model for understanding the endocannabinoid system—and possibly developing better drugs.
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Brain cells found to transfer material to neurons in mice
Researchers have discovered that oligodendrocyte-lineage cells transfer cell material to neurons in a mouse brain. They have provided the first evidence of coordinated nuclear interaction between these cells and neurons.
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2023 drug discovery forecast: emerging trends and disruptors revolutionising the industry
With advancements in artificial intelligence, precision medicine and gene editing, the field of drug discovery is undergoing a rapid transformation. In this article, Drug Target Review’s Izzy Wood gets the insider knowledge from industry leaders at SLAS 2023, who are experiencing these changes first hand.
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Accelerating the immune system could eliminate ageing cells
Boosting the body’s anti-viral immune response could restore tissue balance and eliminate ageing cells that contribute to age-related diseases.
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New drug provides optimism for individuals suffering from heart failure
A newly developed drug displays potential in treating both heart failure and the related sleep apnea.
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Artificial sweeteners weaken mice’s immune response to disease
New findings in mice using artificial sweeteners could result in new therapies to regulate the immune system in those with autoimmune diseases, potentially improving outcomes.
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New shape-shifting antibiotics could solve drug-resistant bacteria
US scientists have developed antibiotics that can “shape-shift”, which prevent bacteria from coming resistant against them.
webinar
Accelerating biologics discovery via antibody library and reaching IND faster with cell line development
4 April 2023 | By GenScript ProBio
The application of Fab and VHH naïve library to expedite the antibody discovery against tumor-associated antigen for CAR-T, ADC and bispecific antibody.
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Researchers develop screening model to evaluate potential cervical cancer drugs
Oregon State University researchers have developed a screening model for rapid testing of multiple drug compounds, using a 3D cellular platform.
whitepaper
Whitepaper: Serum-free and Animal-free Research
Discover how the adoption of animal-free media/supplements can improve reproducibility in cell culture and biotherapeutic research.