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Vaccine to potentially protect against disfiguring skin disease developed
Using CRISPR gene-editing technology, scientists have developed a vaccine designed to prevent infection by Leishmania major.
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Defective mitochondria could be repaired using gene-editing techniques, study finds
Researchers have shown that it could be possible to modify the mitochondrial genome, paving the way for new treatments for incurable mitochondrial diseases.
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New study highlights the possibility to target gene editing in the lungs
Researchers have been able to significantly reduce tumours in a pre-clinical model of a rare genetic lung disease.
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Tool developed to fight cancer rapidly and effectively
Scientists from Northwestern University have developed a new technology platform that could bring individualised cell therapies to cancer patients.
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Findings reveal possible connection to substance use disorders and metabolic dysfunctions
A new study on substance abuse disorders highlights an existing connection between specific neurons and peripheral organs.
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New study could lead to diabetes treatment with fewer side effects
Researchers from the University of Pennsylvania may have discovered how to eliminate the risk of weight gain from certain diabetes medications by uncovering the difference between two varieties of a protein.
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“Monumental” step in using human iPSCs towards treating complication of diabetes
A new study led by the Indiana University School of Medicine showed human induced pluripotent stem cells can improve visual acuity, vascular health and other complications related to type 2 diabetes.
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New research could help design nanocontainers for drug delivery
New research by UC Riverside may be a crucial step in the design of engineered nano-shells that could serve as vehicles for delivering drugs to specific targets in the body.
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New study sheds light on drug-resistance mechanism
MIT chemists have discovered a possible way to design drugs that could fight against drug resistance.
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Scientists ‘reinvent’ petri dish for growing live brain tissue
Researchers have innovated the petri dish to be able to grow and age live brain cells from patients with neurological disorders.
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Possible new class of compounds to treat diabetes identified
A recent pre-clinical study from Washington University School of Medicine showed that a new class of compounds can potentially improve multiple aspects of metabolic syndrome, including diabetes.
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Promising target for osteoporosis treatments found in new study
By identifying a mechanism behind bone strengthening in response to stress, researchers have found a possible new target for treating conditions that weaken bones.
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Pathway to treat type 1 diabetes revealed in study
A new study has identified harmful cellular pathways that prevent insulin production, presenting a drug target for diabetes.
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New research sheds light on what influences target protein binding time
The length of time that drug molecules attach to their target protein varies greatly and impacts the protein’s behaviour and drug efficacy. In a new study, scientists in Finland have identified some causal factors for this variance, with the hope it will bring clarity for drug developers.
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New protein that enables SARS-CoV-2 access into cells identified
Researchers have found that extracellular vimentin facilitates SARS-CoV-2 entry into human cells, presenting a new target.
