video Webinar: Targeting oxygen sensing in cancer 8 January 2021 | By Bio-Techne This webinar from Bio-Techne discusses canonical and alternative oxygen sensing mechanisms implicated in cancer therapy resistance and recurrence.
news Inhibiting acetate metabolism shows promise in breast cancer model 8 January 2021 | By Hannah Balfour (Drug Target Review) Inhibiting the ACSS2 enzyme with a molecule called VY-3-135 caused a significant reduction in the growth of breast cancer tumours in vivo.
news Researchers develop comprehensive database of head and neck cancer 8 January 2021 | By Victoria Rees (Drug Target Review) A new study has revealed a range of genomic, proteomic and transcriptomic data about head and neck cancers, presenting possible treatment strategies.
article A single approach to creating effective cancer and autoimmune disease therapeutics 8 January 2021 | By Dr H Michael Shepard (Enosi Life Sciences) Dr H. Michael Shepard, CEO and CSO of Enosi Life Sciences, discusses the similarities between cancer and autoimmune diseases, highlighting how this knowledge could be used to enhance treatments.
news Bioactive compound in ginger could be used in treatment of lupus 7 January 2021 | By Victoria Rees (Drug Target Review) According to new research, the bioactive compound of ginger root, 6-gingerol, prevented disease progression of lupus in mice.
news Exploration of autoimmune disease target tissues reveals novel drug targets 7 January 2021 | By Hannah Balfour (Drug Target Review) Researchers suggest that identifying new treatments for autoimmune diseases requires studying the immune system AND target tissues together.
news New drug target for non-small cell lung cancer identified 6 January 2021 | By Victoria Rees (Drug Target Review) A new study has suggested that the enzyme GFPT2 could be a useful target for non-small cell lung cancer (NSCLC).
news NIK could be key to enhancing the effects of immunotherapy 6 January 2021 | By Hannah Balfour (Drug Target Review) Immunology study shows that NF-kappa B-inducing kinase (NIK) is critical to T cell metabolism and the antitumour immune response.
news Novel prostate cancer resistance mechanism could be a promising target 6 January 2021 | By Hannah Balfour (Drug Target Review) By inhibiting the activity of microRNA-194 (miR-194), scientists prevented prostate cancer cells from developing treatment resistance in vitro.
news Potential probiotic treatment identified for type 2 diabetes 5 January 2021 | By Victoria Rees (Drug Target Review) Researchers have identified microbes that could affect the way a person metabolises glucose and lipids, leading to a potential treatment for type 2 diabetes.
news Brain injury may drive the development of cancer 5 January 2021 | By Hannah Balfour (Drug Target Review) A new study reveals that the healing process following a brain injury could initiate the growth of glioblastoma cancers.
news Novel bronchodilator could be used for control of asthma 5 January 2021 | By Hannah Balfour (Drug Target Review) Study identifies a promising new compound that can open constricted airways and could be a promising treatment for obstructive lung diseases.
news Activating STING enhances CAR T-cell activity in solid tumours, shows study 4 January 2021 | By Hannah Balfour (Drug Target Review) Researchers were able to eradicate breast cancer in mice when they combined CAR T cells with STING pathway agonists and immunotherapeutic antibodies.
article COVID-19 drug development based on boosting immunity 31 December 2020 | By Baidyanath Dash (G3 Systems) Baidyanath Dash explains the two requirements for COVID-19 drug development: killing the virus and boosting immunity.
article A computational effort to deciphering putative COVID-19 3C-like protease binders 28 December 2020 | By Dr Isaac Karimi (Razi University) Dr Isaac Karimi and his team explain how compounds to treat COVID-19 could be found in Kurdish ethnomedicine, selecting some plants for computational drug discovery.
