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Cancer cell nutrient pathway mechanism discovered
Researchers have discovered the mechanism behind a gateway into cells for glutamine, illuminating potential ways to prevent cancer cells from getting nutrients.
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Researchers discover new neuroblastoma drug target
A study has discovered that reducing expression of a key gene in neuroblastoma tumourigenesis is an important drug target for the condition.
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Study identifies potential drug target for prostate cancer
Researchers have discovered a non-coding RNA which could be used as a biomarker and in new therapies for prostate cancer.
news
No-cut CRISPR could be used to treat muscular dystrophy
Researchers have successfully used a no-cut CRISPR gene editing technique as a therapy for muscular dystrophy in mice models.
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Encouraging drug discovery and therapeutic targets for dementia
A review has been published by experts in neurodegeneration research, detailing six ways to improve dementia research. This article investigates one of these suggestions, focusing on how we can improve drug target identification.
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Screening identifies gene which protects cells from Zika virus
Researchers used screening to discover genes that protect the body against the Zika virus, which could inform potential therapies against the virus.
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Study discovers key process in the cause of cell aging
Researchers have identified a key process behind senescence, or why cells age, which could be used to improve treatments for cancer.
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Scientists control living cells using artificial protein switch
Scientists have created the first completely artificial protein switch that can be ‘programmed’ to modify gene expression.
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‘Reverse vaccinology’ used to create novel HIV treatment
Researchers have developed a new HIV vaccine which has shown success in monkeys in pre-clinical trial studies.
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Study finds fat cells play key role in melanoma metastasis
Researchers have found that fat cells transfer cytokines to melanoma cells, which transforms them into aggressive tumours, indicating a drug target for the condition.
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Method for inhibiting tumour growth enzyme discovered
A new study has found a novel way to target an enzyme involved in cancer growth, which could inform therapeutics for the condition.
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Experimental compound slows blood cancer growth
Researchers have identified a protein that plays a role in promoting blood cancer and have successfully used a novel compound to inhibit it, reducing tumour growth.
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Genes linked to cell survival during sepsis identified
Researchers have found a set of genes which helps cells survive during sepsis in mice and could inform potential treatments for the condition.
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Promising drug developed for ovarian and pancreatic cancers
An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.
whitepaper
Whitepaper: CD4+ T-Cell Subsets
CD4+ T-cells play a central role in directing adaptive immune responses against invading microbial pathogens.
