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Reprogramming stem cells using the measles virus vector
A method has been developed to reprogram stem cells using the measles virus vector, cutting a four-step process to only one stage...
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Functional transplantable B-cells generated from mice
Stem cells generated from mice have shown to be functional when transplanted, leading to the possibility of future therapies...
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The role of immune cells in metastasis
Specific immune cells, such as neutrophils, have been found to aid the progression of cancers, promoting metastasis in tumours...
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Treatment could prevents and treat Chlamydia
The development of a treatment that prevents and treats Chlamydia uses nanotechnology, and could change the way the disease is treated...
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Key function of specialised cells in peripheral nerve repair
The interaction between macrophages and Schwann cells could be vital in maintaining the repair process, without which could impair nerve function...
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Genetic sequence can predict protein production efficiency
Protein produced in a cell is crucial to maintaining the function of the organism, and this function is important to understand numerous human diseases...
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Mucus could be key to treating colon and airway diseases
The action of proteins that control mucus production could suggest clues to treating colon and airway conditions such as asthma or Crohn's disease...
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The path of metallodrugs in breast cancer cells
The path a metallodrug uses to target and kill cancer cells could be used to design drugs to target triple-negative breast cancer...
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Clusterin linked to both cardiac and metabolic diseases
The protein clusterin has been linked to different cardiometabolic syndrome risks, with researchers asking whether it could be a therapeutic target...
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Engineered dl355 virus has the potential to be an effective anticancer treatment
An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers...
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Drug compound could be next-generation treatment for aggressive form of AML
Researchers have developed a series of compounds that work not only on AML with common FLT3 mutation but also drug-resistant AML...
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New drug targets for BRCA-driven cancer uncovered
Preclinical study yields previously unreported, potent and generalisable hits representing potential drug targets for hereditary breast, ovarian cancer...
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DNA anticancer vaccine targets tumour neoantigens
A DNA vaccine developed through the use of unique tumour antigens could lead the way towards vaccinating people against cancer...
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Catching lung cancer early using molecular profiling
Researchers have identified how they can differentiate between lesions in the airways that are benign and those that could become cancerous...
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Gene responsible for prostate cancer spread identified
Identified using a computer algorithm, the NSD2 gene may be responsible for advancing the spread of prostate cancer, and so could be used as a drug target...
