List view / Grid view
Enzymes are macromolecular biological catalysts. Enzymes accelerate, or catalyse, chemical reactions.
21 May 2015 | By Victoria White
Researchers have identified three genes that play a pivotal role in choroid plexus carcinoma, a discovery that could lead to more effective treatment...
11 May 2015 | By Victoria White
US and EU Patent Offices have granted Domainex patents for the first generation of inhibitor compounds in its lead programme targeting IKK epsilon and TBK1.
29 April 2015 | By Victoria White
Inhibiting HDACs has shown significant potential in stimulating the growth of brain cells and memory restoration in animal models that mimic Alzheimer’s...
28 April 2015 | By Victoria White
A team at CSHL has published results of experiments that lay bare a previously unknown pathway activated in HER2-positive breast cancer...
30 March 2015 | By Victoria White
Around 6.5 million Europeans currently suffer from AMD. Nanoparticles could potentially be used as carriers for drug treatments instead of injections...
19 March 2015 | By Victoria White
MISSION Therapeutics announces the appointment of Paul Wallace PhD as Chief Business Officer...
8 December 2014 | By Codexis
Codexis, Inc. announced that it has developed a novel enzyme therapeutic product candidate for the potential treatment of phenylketonuria (PKU) via oral administration...
2 December 2014 | By The Medical Research Council
Medical Research Council scientists have created the world’s first enzymes made from artificial genetic material...
Macrocyclic compounds (see Figure 1) have fascinated medicinal chemists for generations. The first ones which have been characterised are the naturally occurring cyclodextrins (CDs), cyclic oligomers of glucose, which can be obtained by bacterial synthesis from starch. Calixarenes (CXs) were among the first man-made macrocycles, followed by crown ethers (Pedersen,…
30 September 2014 | By Daiichi Sankyo
Lead compound, Quizartinib, will further build Daiichi Sankyo oncology pipeline...
9 July 2014 | By Boehringer Ingelheim
Results from a Phase II study, published in the American Society of Hematology journal Blood, showed patients with previously untreated acute myeloid leukemia aged 65 or older and ineligible for intensive remission induction therapy, lived longer...
The ubiquitin-proteasome system (UPS) is a hierarchical enzymatic cascade that plays an essential role in a broad range of cellular pathways and is found in cytoplasmic and nuclear actions of all eukaryotic cells...
Despite the ever increasing efforts being expended for drug discovery purposes, the number of approved drugs remains relatively static. A variety of explanations have been provided to explain this observation and initiatives to remedy this situation have been implemented. Many of these initiatives are still works-in-progress and whether these will…
