Researchers discover clues on how cells control their volume
A new study from the University of Pittsburgh and Carnegie Mellon University may solve the puzzle of how cells control their volume.
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Enzymes are macromolecular biological catalysts. Enzymes accelerate, or catalyse, chemical reactions.
A new study from the University of Pittsburgh and Carnegie Mellon University may solve the puzzle of how cells control their volume.
Researchers have found that blocking key enzymes could boost anti-cancer T cell responses and resistance to immunosuppression.
The findings by Massachusetts General Hospital could point to a potential target to treat Crohn’s disease.
Researchers have found that an already existing drug compound could block the activity of a key enzyme of COVID-19.
A new study has highlighted an enzyme called ART1 as a promising target for immunity-boosting cancer treatments.
Using chemical genetic screening and pre-clinical model studies, researchers have discovered that inducing ubiquitin-mediated degradation of mutant EZH2 could provide a more effective treatment strategy for haematologic malignancies.
A new study in the US has used a computer model to reveal the mechanism of action of lipoprotein-associated phospholipase A2 – a biomarker for cardiovascular disease.
A microplate-based method for the determination of association and dissociation rate values in high throughput using a kinetic probe competition assay (kPCA).
All mice infected with anthrax spores were completely protected after treatment with a pegylated enzyme known as PEG-CapD-CPS334C.
Scientists used a CRISPR-based screen to find that inhibiting MTHFD2 reduces disease severity in inflammatory disease models.
Scientists have discovered a novel pathway and enzyme that causes thrombosis in chronic kidney disease (CKD) patients, indicating a new drug target.
In a new study, a calorie-restricted diet significantly reduced tumour growth in mouse models, suggesting new possibilities for cancer therapies.
Researchers are identifying molecules that interact with neurolysin, a peptidase that helps protect the brain against stroke.
Lipophosphonoxins may represent the next generation of antibiotics and can be delivered using a new type of dressing for skin wounds.
The new CRISPR-based technology called MIC-Drop rapidly identified several genes for heart development and function in zebrafish.