news
Artificial enzyme catalytic capabilities improved, say researchers
A study has shown that using a particular three-stranded structure can extend the catalytic performance of artificial metalloenzymes.
List view / Grid view
Enzymes
Enzymes are macromolecular biological catalysts. Enzymes accelerate, or catalyse, chemical reactions.
news
Drug discovered for Postural Orthostatic Tachycardia Syndrome (POTS)
A novel therapy, tested ex vivo, has been successful at correcting the dysfunctional body mechanism in Postural Orthostatic Tachycardia Syndrome (POTS).
news
Researchers identify enzyme critical for regulating cell signalling
An enzyme that adds a cell-signalling code to proteins has been identified by researchers, who say their discovery could aid in the development of cancer therapies.
news
Novel compound to kill malaria parasites developed by researchers
A collaborative team has developed a compound called WM382, which targets two crucial enzymes in the malaria parasite, effectively killing it.
news
Mechanism of action revealed for remdesivir, potential coronavirus drug
Researchers have demonstrated how the drug known as remdesivir works, presenting the viral RNA polymerase of coronaviruses as a target for these conditions.
news
Researchers find drug improves cancer immunotherapy in mice
A study has shown that in mice, the GKT137831 drug makes tumours more sensitive to immunotherapy, so could be used to improve cancer treatments.
news
Researchers gain new insight into LRRK2 – a potential cause of Parkinson’s
Scientists in the US have applied a novel technique to finally unravel a particular kinase enzyme that is associated with familial Parkinson’s disease; providing a clearer potential therapeutic target.
news
Researchers suggest IMPDH enzyme could be used to target sleeping sickness
Research into drug targets for sleeping sickness parasite T. brucei has characterised the inosine-5'-monophosphate dehydrogenase (IMPDH) enzyme, providing a possible novel avenue for therapies.
news
Putrescine could be a therapy for chronic inflammatory diseases
Research has identified that putrescine, which aids macrophages in clearing dead cells, is lacking in atherosclerosis animal models and could be a potential therapeutic for the condition.
news
PCSK6 enzyme plays a key role in vascular disease, according to research
A new study has demonstrated that the enzyme proprotein convert subtilisin/kexin 6 causes structural and functional remodelling in vascular disease, so could be a new therapeutic target.
news
Scientists find leukaemia’s Achilles heel in vitamin B6
A possible new avenue for treatment of Acute Myeloid Leukaemia (AML) has opened up after US scientists pinpoint how the cancer spreads using excessive amounts of vitamin B6.
news
Synthetic enzyme combats disorders caused by dysfunctional mitochondria
Researchers have developed a new enzyme that prevents electron build-up in cells caused by aberrant mitochondria which could be a therapeutic technique for rare genetic conditions.
news
Genes found to slow down the development of intestinal tumours
Scientists have found that when two specific genes are deleted in benign tumour tissue in the intestines, it more rapidly develops into a tumour that is more likely to become cancerous.
news
First images of an ‘upgraded’ CRISPR tool captured
Researchers have utilised cryo-electron microscopy and used the images they captured with an electron microscope to generate atomic resolution models of the INTEGRATE system.
news
Origins and potential therapies for a neurodegenerative disorder found
Various potential therapeutic opportunities to treat spinocerebellar ataxia type 7 (SCA7) have been discovered in a new study into the neurodegenerative disorder.