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Scientists discover the key to hepatitis A virus replication
With no current treatments for hepatitis A, scientists have discovered how a protein and enzymes interact to allow hepatitis A virus to replicate.
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Gene Testing
Gene testing is a type of medical test that identifies changes in chromosomes, genes, or proteins.
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Concerns for future gene therapy testing in laboratory mice
Researchers have found that new sickle cell disease gene therapies depend on choosing the right laboratory mice.
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Building artificial Hox genes
Researchers have created artificial Hox genes using new synthetic DNA technology and genomic engineering in stem cells.
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An effective and error-free gene editor
Scientists have developed a new gene editor which uses a modified pair of molecular scissors that make nicks on opposite strands of the DNA at two different points.
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Gene discovery indicates motor neurone diseases caused by abnormal lipid processing in cells
A new genetic discovery adds weight to a theory that motor neurone diseases are caused by abnormal lipid processing pathways inside brain cells.
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Target protein for diabetes drug linked to reduce the risk of Alzheimer’s disease
Scientists from Karolinska Institutet have found mechanisms associated with a particular diabetes drug that can also help to protect against Alzheimer’s disease.
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Study suggests postnatal gene therapy could treat Pitt-Hopkins syndrome
Researchers have found that restoring lost gene activity prevents many disease signs in an animal model of Pitt-Hopkins syndrome.
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CRISPR-dCas9 gene editing reverses brain genetic reprogramming caused by adolescent binge drinking
A new study in animals has shown that gene editing may be a potential treatment for anxiety and alcohol use disorder in adults who were exposed to binge drinking in their adolescence.
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Gene therapy: A potential cure for growth-hormone resistant dwarfism
Researchers have shown that gene therapy using a single-dose injection of a virus carrying the ‘good’ gene could possibly be used to cure growth-hormone resistant dwarfism.
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Using CRISPR to improve lung cancer treatments
Scientists have developed CRISPR with a new process that evaluates the impacts of gene edits that alter rather than deleting DNA code.
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Researchers use brain organoids to identify neural abnormalities and test gene therapy tools
Scientists used human brain organoids to reveal how a genetic mutation associated with a profound form of autism disrupts neural development, and gene therapy tools to recover the gene’s function effectively rescued neural structure and function.
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Study shows muscular dystrophies can be repaired with CRISPR-Cas9
Researchers have introduced a CRISPR-Cas9 tool into human muscle stem cells using mRNA, thus discovering a suitable method to treat muscular dystrophies.
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An epigenetic cause of miscarriages has been identified and cured in mice
Researchers have discovered that failed epigenetic suppression of an X-chromosome gene called Xist leads to miscarriage and developmental abnormalities.
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Scientists create brain organoids to understand autism
Researchers have been using brain organoids to understand how a mutated gene affects the brain at its very early stage of development.
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A revolutionary technique to rejuvenate skin cells
Researchers have developed a new method to rewind the age of skin cells by 30 years without losing their specialised functions.