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Two-faced protein both inhibits and activates B cell receptor signalling
New research could point towards a way to restore immune function in patients with immune disorders involving B cell signalling deficiencies.
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Gene Testing
Gene testing is a type of medical test that identifies changes in chromosomes, genes, or proteins.
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New CRISPR gene-editing technology could lead to better treatments for HIV
Scientists at Northwestern Medicine have developed new techniques in human blood to pave potential paths towards a HIV cure.
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Novel genome-wide approach to engineer more effective immunotherapy
Scientists have developed a genetic screening platform to identify genes that can enhance immune cells to make them more persistent and increase their ability to eradicate tumour cells.
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Research collaboration to study ageing reversal in liver tissue established
Genflow have announced a scientific research collaboration with the University of Rochester’s Aging Research Center. Together, they will study the ageing process in liver tissue.
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New genetic model of Down’s syndrome developed in rats
Scientists have created what they believe is the first rat model of Down’s syndrome. The animal model shares features with human Down’s syndrome, which will allow for efficient testing of new therapies.
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Pre-clinical study shows significant increase in effectiveness of breast cancer immunotherapy
Scientists have discovered the essential role of a ligand-dependent corepressor to potentially enable cancer cells to present tumour antigens on their surfaces.
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Vaccine to potentially protect against disfiguring skin disease developed
Using CRISPR gene-editing technology, scientists have developed a vaccine designed to prevent infection by Leishmania major.
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Defective mitochondria could be repaired using gene-editing techniques, study finds
Researchers have shown that it could be possible to modify the mitochondrial genome, paving the way for new treatments for incurable mitochondrial diseases.
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New study highlights the possibility to target gene editing in the lungs
Researchers have been able to significantly reduce tumours in a pre-clinical model of a rare genetic lung disease.
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Study identifies key regulator of cell differentiation
Long-awaited findings about cell differentiation will be relevant in understanding normal development and may also be useful in cancer research.
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Moderna and Metagenomi to develop in vivo gene therapies
Moderna and Metagenomi have announced a collaboration to jointly create next-generation in vivo gene editing therapeutics.
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CRISPR-Cas9-based gene dropout screens: a powerful platform for drug discovery
CRISPR holds great promise in advancing pharmacological research and has fuelled the rapid expansion of using gene-edited cells for drug discovery processes. CRISPR-Cas9 dropout screens have emerged as a useful tool for high-throughput large-scale loss-of-function screens, which seek to identify the relationship between genotype and phenotype. Dr Pushpanathan Muthuirulan, Research…
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Application note: Streamlined genome engineering in picodroplets
A picodroplet-based microfluidic method for automating the complete genome-editing workflow. Learn more in this free application note.
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Scientists create organoid biobank to study SARS-CoV-2 genes
Researchers have established an organoid biobank to search for genes that are essential for the spreading of SARS-CoV-2 infection.
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Novel technology could significantly advance genomics field
New technology system of drug-based markers for the selection or counter-selection of genes may advance genetic screening methods.