news
EU conditional marketing authorisation announced for ZYNTEGLO
ZYNTEGLO™ is the first gene therapy approved for transfusion-dependent β-thalassemia (TDT).
List view / Grid view
Gene Therapy
Gene Therapy is the introduction of normal genes into cells in place of missing or defective ones in order to correct genetic disorders.
news
Genetic therapy can heal damage caused by a heart attack
Researchers from King's College London have found a method that can induce heart cells to regenerate after a heart attack.
news
Colon cancer proteins and gene analysis uncovers potential new treatments
A new study analysing both the entire set of genes and all the proteins produced by colon cancer tissues has revealed a more comprehensive view of the tumour.
news
New nanomachines developed to deliver cancer drugs to hard-to-reach areas
In a recent study in mice, researchers have found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access.
news
Artificial chemical receptor developed to assist in T cell engineering
Engineered T cell immunotherapy (such as chimeric antigen receptor T cell (CAR-T) and T cell receptor T cell (TCR-T) therapy), could potentially be used as a therapeutic strategy for tumour treatment.
news
Scientists home in on microRNA processing for cancer therapies
Research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs...
news
Gene therapy to reduce deafness in mice
Gene therapy has been used to restore hearing in an adult mouse model of DFNB9 deafness, one of the most frequent cases of congenital genetic deafness...
whitepaper
Application note: Direct measurements of cellular metabolism for identification of mitochondrial drug targets
Drug target identification has a key role in the drug discovery value chain. A critical step in the development of pharmaceuticals is identifying the direct targets of potential drug candidates as well as distinguishing any secondary or off-target effects...
whitepaper
Application note: automated cell transfection and reporter gene assays
Reporter gene assays have greatly helped our understanding of gene regulation and signal transduction in vitro and in vivo.
news
Micropeptide molecule restores heart function
A micropeptide molecule that reverses structural and functional changes in the heart could be a promising target for gene therapy...
news
Mitochondrial diseases could be treated with gene therapy
Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases...
whitepaper
Application Note: Full-length, single-cell RNA-seq with the SMARTer™ ICELL8® Single-Cell System
6 September 2018 | By Takara Bio
The data presented in this application note demonstrates how SMARTer ICELL8 Single-Cell System can be used to generate high-quality RNA-seq libraries that provide full-length transcript sequence information from hundreds of single cells in parallel...
news
A step closer to preventing autoimmune response to gene therapy
Scientists in the U.S. have demonstrated an effective means of administering gene therapy in mice, without the dangerous autoimmune reaction that often occurs.
news
Nuclear medicine technique to gauge impact of gene therapy
A new molecular imaging method can monitor the success of gene therapy in all areas of the brain, potentially allowing physicians to more effectively address brain conditions such as Parkinson's disease, Alzheimer's disease and multiple sclerosis.
news
ISSCR 2018 to highlight research driving new discoveries and advances in regenerative medicine
Progress in stem cell research and its translation to medicine is the focus of the International Society for Stem Cell Research annual meeting 20-23 June at the Melbourne Convention & Exhibition Centre in Melbourne, Australia.
