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New nanomachines developed to deliver cancer drugs to hard-to-reach areas
In a recent study in mice, researchers have found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access.
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Gene Therapy
Gene Therapy is the introduction of normal genes into cells in place of missing or defective ones in order to correct genetic disorders.
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Artificial chemical receptor developed to assist in T cell engineering
Engineered T cell immunotherapy (such as chimeric antigen receptor T cell (CAR-T) and T cell receptor T cell (TCR-T) therapy), could potentially be used as a therapeutic strategy for tumour treatment.
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Scientists home in on microRNA processing for cancer therapies
Research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs...
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Gene therapy to reduce deafness in mice
Gene therapy has been used to restore hearing in an adult mouse model of DFNB9 deafness, one of the most frequent cases of congenital genetic deafness...
whitepaper
Application note: Direct measurements of cellular metabolism for identification of mitochondrial drug targets
Drug target identification has a key role in the drug discovery value chain. A critical step in the development of pharmaceuticals is identifying the direct targets of potential drug candidates as well as distinguishing any secondary or off-target effects...
whitepaper
Application note: automated cell transfection and reporter gene assays
Reporter gene assays have greatly helped our understanding of gene regulation and signal transduction in vitro and in vivo.
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Micropeptide molecule restores heart function
A micropeptide molecule that reverses structural and functional changes in the heart could be a promising target for gene therapy...
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Mitochondrial diseases could be treated with gene therapy
Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases...
whitepaper
Application Note: Full-length, single-cell RNA-seq with the SMARTer™ ICELL8® Single-Cell System
6 September 2018 | By Takara Bio
The data presented in this application note demonstrates how SMARTer ICELL8 Single-Cell System can be used to generate high-quality RNA-seq libraries that provide full-length transcript sequence information from hundreds of single cells in parallel...
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A step closer to preventing autoimmune response to gene therapy
Scientists in the U.S. have demonstrated an effective means of administering gene therapy in mice, without the dangerous autoimmune reaction that often occurs.
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Nuclear medicine technique to gauge impact of gene therapy
A new molecular imaging method can monitor the success of gene therapy in all areas of the brain, potentially allowing physicians to more effectively address brain conditions such as Parkinson's disease, Alzheimer's disease and multiple sclerosis.
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ISSCR 2018 to highlight research driving new discoveries and advances in regenerative medicine
Progress in stem cell research and its translation to medicine is the focus of the International Society for Stem Cell Research annual meeting 20-23 June at the Melbourne Convention & Exhibition Centre in Melbourne, Australia.
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Expert view: Discovering neuronal cell types
Target the genes that matter for efficient sequencing and analysis with custom-targeted gene panels.
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Expert view: Screening tools for better lead characterisation
Predictiveness is one of the key factors for success in the drug discovery workflow. Many compounds fail at late stages due to lack of predictive data or the discovery of unwanted side effects.
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Explore next generation therapeutics and ATMPS in May
The 13th annual World Advanced Therapies & Regenerative Medicine Congress brings together 1000+ attendees and explores the rapidly developing world of next generation therapeutics and ATMPS.
