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Gene therapy may lower risk for heart disease
Researchers have tested whether a single injection of the gene, LeXis could slow down the development of heart disease...
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Gene Therapy
Gene Therapy is the introduction of normal genes into cells in place of missing or defective ones in order to correct genetic disorders.
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£2m collaboration to focus on gene and cell therapy
A leading gene and cell therapy group has announced a collaboration focusing on gene and cell therapy manufacturing..
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From cancer evolution to personalised therapies
A research team have studied how alterations in a tumour depend on each other and how these dependencies determine cancer evolution...
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Biological bypass shows promise in coronary artery disease
A new gene therapy that targets the heart and requires only one treatment session has been found safe for patients with coronary artery disease...
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CRISPR identifies essential genes for cancer immunotherapy
Researchers have used CRISPR to stop the expression of individual genes in cancer cells, by knocking out every known protein-encoding gene in the human genome...
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CRISPR-Cas9 repairs genetic mutation in human embryos
"Well thought through and brilliantly executed" study shows different DNA-repair mechanism in embryos compared to iPSCs
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Researchers find new genes link to arthritis in bone marrow lesions
Researchers have found a pattern of genes which is characteristic of osteoarthritis and may be a step towards better treatments for this condition.
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Largest genome-wide study of lung cancer susceptibility conducted
A new study conducted by an international team of lung cancer researchers have identified new genetic variants for lung cancer risk.
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Ryboquin raises £1.8m for drug development in gene therapy
This latest funding round attracts two prominent new investors; Brian Kennedy and Sir Brian Souter.
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Dynamic DNA helps ward off gene damage
MRC-funded researchers have identified properties in DNA’s protective structure that could transform the way scientists think about the human genome.
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Queen’s researchers breakthrough discovery in fight against bowel cancer
New research led by Queen’s University Belfast has discovered how a genomic approach to understanding bowel cancer could improve the prognosis and quality of life for patients.
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CRISPR gene editing can cause hundreds of unintended mutations
As CRISPR-Cas9 starts to move into clinical trials, a new study has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.
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Breakthrough in better understanding of acute myeloid leukaemia
A study led by the University of Birmingham has made a breakthrough in the understanding of how different genetic mutations cause acute myeloid leukaemia.
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Largest psoriasis meta-analysis to date yields new genetic clues
1-2% of the US population have psoriasis, an immune-mediated disease that causes red, patchy and scaly marks on the skin.
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Control mechanism unveiled for gene that causes Opitz syndrome
Opitz G/BBB (Opitz) syndrome is a hereditary disorder that affects people in different ways, causing malformations in medial (midline) organs and structures, intellectual disability and developmental disorders.