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How data science is driving genomics in the pharmaceutical industry
In this article, Ramya Sriram describes how data science is driving innovations in medical biotechnology and genomics.
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Genetic Analysis
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New SARS-CoV-2 strain identified in South East England
UK Health Secretary Matt Hancock has said there is a mutated form of SARS-CoV-2 that may be causing a rise in infections in South East England.
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Role of gene in metastasis of brain cancer revealed
Researchers have shown how increased YTHDF3 expression correlates with brain cancer metastases, making it a target for the condition.
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Tracking SARS-CoV-2 with genome sequencing
Researchers have been tracking SARS-CoV-2 by sequencing the genomes of virus samples collected from diagnostic testing. They hope that using next-generation sequencing (NGS) on SARS-CoV-2 will help to accurately diagnose the novel coronavirus, identify mutations and track its history. This article explores the findings of their latest study and what…
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Genetic screening to predict the risk of future diseases
The use of genetic testing has had a positive impact on patient care, bringing abundant opportunities for diagnosis or predictions of future diagnoses. Pushpanathan Muthuirulan explains how the application of genetic screening can help to customise healthcare for individuals based on their unique genetic makeup.
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Predicting COVID-19 susceptibility and severity
Recent reports suggest that both clinical and genetic risk factors may contribute to COVID-19 susceptibility and severity. Catherine Ball, Chief Scientific Officer of Ancestry®, discusses results of the company’s COVID-19 Research Study, designed to explore non-genetic and genetic associations with disease outcomes.
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Tweaking synonymous sites for gene therapy and vaccines
Professor Laurence D Hurst explains why understanding the nucleotide mutations in viruses, including SARS-CoV-2, can have significant implications for vaccine design.
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SARS-CoV-2 mutations do not increase transmissibility, research shows
Having analysed the SARS-CoV-2 genomes from over 46,723 patients, researchers have found no mutations that increase transmissibility.
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CD209 antigen could be a promising target for preventing severe COVID-19
Researchers reveal how two genetic variations may contribute to COVID-19 disease severity and suggest the product of one, the CD209 antigen, may be a potential drug target.
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Proteogenomic analysis offers insights into paediatric brain tumours
The first comprehensive survey of genomics, transcriptomics, global proteomics and phosphoproteomics has revealed insights into paediatric brain tumours.
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Screening In-Depth Focus 2020
In this in-depth focus find out how genetic screening can be used to customise healthcare and why scientists have turned to machine learning in the fight against antimicrobial resistance.
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Epidemiological data on SARS-CoV-2 uncovers insights into mutations
Researchers have analysed 750 samples from patients with SARS-CoV-2 to discover details about its transmission and mutational properties.
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RNA structures of SARS-CoV-2 reveal potential drug targets
The SARS-CoV-2 RNA genome structure has been studied by researchers who identified several potential drug targets.
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Role of retrons in bacteria revealed, with potential for use in gene editing
The role that retrons in bacteria has been discovered by researchers, who found they protect colonies when infected by viruses.
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D614G mutation may make SARS-CoV-2 more contagious
According to a new study, the SARS-CoV-2 virus is accumulating genetic mutations, including one called D614G which may have made it more contagious.
