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Genetic Analysis

Pancreatic cancer: specific protein promotes development of pancreatitis and tumours

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Pancreatic cancer: specific protein promotes development of pancreatitis and tumours

6 December 2017 | By Drug Target Review

A study has shown that disruption to cell autophagy is involved in the development of pancreatic cancer.

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DNA sequencing demonstrates use for treatment of chronic kidney disease

5 December 2017 | By Drug Target Review

Results from a new study suggest that DNA sequencing could soon become part of the routine diagnostic examination for patients with chronic kidney disease.

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CRISPR engineered to edit single RNA letters

26 October 2017 | By Dr Zara Kassam (Drug Target Review)

New 'REPAIR' system edits RNA, rather than DNA, without permanently affecting the genome...

news

MMP20 gene variants linked to high-risk childhood cancers

26 September 2017 | By Dr Zara Kassam (Drug Target Review)

Paediatric researchers have identified common gene variants that raise the risk of an aggressive forms of childhood cancer...

news

Cytokine molecules unearth development of progressive MS

19 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have uncovered two closely related cytokines molecules involved in cell communication that explain why some people develop progressive MS...

news

KDM4 inhibitor brings new hope for breast cancer

15 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have shown that inhibiting the epigenetic regulator KDM4 may offer a potential novel treatment for breast cancer...

news

Genetic testing leads to response in MET fusion lung cancer

1 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a rare fusion involving the gene MET leading researchers to treat the cancer with a targeted therapy...

news

Sequencing all 24 human chromosomes uncovers rare disorders

31 August 2017 | By Dr Zara Kassam (Drug Target Review)

Study from NIH may help improve prenatal genetic screening...

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GIST tumours linked to NF1 mutations

21 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have determined that a specific region of the duodenal-jejunal flexure, shows a high frequency of gastrointestinal stromal tumours with mutations of the NF1 gene...

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New genetic analysis reveals early diagnosis for breast cancer

15 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have shown that catching and treating breast cancer before it spreads is now a realistic goal...

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Improved analysis of kidney cancer

11 August 2017 | By Dr Zara Kassam (Drug Target Review)

A research team have discovered that in the Cancer Genome Atlas database the gene expression in reference samples differs from normal tissue, depending on where in the kidney the samples happen to have been taken from...

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NIH accelerates the use of genomics in clinical care

9 August 2017 | By Dr Zara Kassam (Drug Target Review)

The National Institutes of Health is awarding $18.9 million towards research that aims to accelerate the use of genome sequencing in clinical care...

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CRISPR identifies essential genes for cancer immunotherapy

8 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used CRISPR to stop the expression of individual genes in cancer cells, by knocking out every known protein-encoding gene in the human genome...

news

Genetic testing may detect childhood epilepsy

31 July 2017 | By Dr Zara Kassam (Drug Target Review)

Specific genetic factors have been found to be the cause of epilepsy in 40 percent of patients evaluated with seizures...

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Researchers find new genes link to arthritis in bone marrow lesions

19 July 2017 | By Niamh Marriott (Drug Target Review)

Researchers have found a pattern of genes which is characteristic of osteoarthritis and may be a step towards better treatments for this condition.

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Genetic Analysis