Study concludes that most aspects of aging relate to gene length
New findings about how long genes become less active with age could impact treatments for neurodegeneration, among other conditions.
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New findings about how long genes become less active with age could impact treatments for neurodegeneration, among other conditions.
Using in situ sequencing, a collaborative research group analysed 260 genes and discovered new sub-structures in MS lesions.
The findings from DNA and RNA sequencing in primary and metastatic UTUC tumours could lead to strategies to improve patient outcomes.
In this Q&A, Dr Murray Cairns, NHMRC Leadership Research Fellow at the University of Newcastle, shares his insights about the genetic influences on circulating retinol, and explains how a retinol polygenic score could be utilised in a precision medicine approach.
Scientists have examined gene activity in mice models, noting important indicators of liver disease severity which may be used as therapeutic strategies.
A condensed version of the SMN2 gene could improve discovery of potential therapies for spinal muscular atrophy and other conditions.
Researchers have identified that AF1q is highly expressed in neuroblastoma, and could be used to destabilise N-Myc.
Researchers have gained a better understanding of the genes and biological processes that could influence POAG pathogenesis.
Researchers have discovered the role of two genes that protect mammalian germ cells, which could influence male fertility.
Distinct macrophage signatures that align specifically with regeneration could offer novel therapies to enhance wound healing.
A deep learning model developed using circulating cell-free DNA outperformed traditional screening methods for gestational diabetes mellitus.
A new project plans to elucidate the relationship between the glucosylceramidase beta gene and Parkinson’s disease.
PLK4 inhibition could be a novel therapeutic for an acute myeloid leukaemia subtype carrying the TP53 mutation.
The ML algorithm explores how genetic mutations collectively influence a tumour’s reaction to drugs impeding DNA replication.
A potential link between truncating variants and the development of DCM has been found, and a patient-focused registry about PPCM was made.