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A new way to visualise sensory neurons
US researchers have uncovered a novel method using a tool used to visualise ion channels in mechanosensory neurons.
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Genetic Analysis
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$6 Million grant issued to Penn Medicine to investigate role of DNA in cardiac cell development
Penn Medicine researchers are interested in how cardiac cells use DNA to establish and maintain their specification.
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Precision oncology aids prospects for biliary tract cancer
A study out of Austria suggests gene changes in those with biliary tract cancer offers new avenues for new precision oncology therapies.
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Nerve regeneration offers hope for blindness and paralysis
US researchers uncover that certain nerve cells that have the capacity to regrow, are necessary for axon regeneration, providing hope for conditions like blindness and paralysis.
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Novel mutation linked to late-onset Alzheimer’s disease
Chinese researchers discover a mutation, referred to as the "Shanghai APP" mutation, which has been linked to late-onset Alzheimer's disease and offers fresh insights into the disease's underlying molecular mechanisms.
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Scientists create first humanised mouse model for rare genetic disease
German researchers have successfully developed mice with a defected human gene responsible for congenital adrenal hyperplasia (CAH), a rare genetic disease.
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New algorithm can predict diabetic kidney disease
Researchers from US and Hong Kong have found that a simple blood sample may help doctors catch kidney disease earlier in type 2 diabetes patients
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Novel approach stimulates DNA repair mechanisms to combat a leading cause of autism spectrum disorders
US researchers report promising results for fragile X syndrome, by stimulating cells' DNA repair mechanisms that could correct the inherited genetic defect associated with the disorder.
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Targeted therapy for treatment-resistant breast cancer
US researchers have uncovered a potential target for treating breast cancer that is resistant to endocrine therapies because of a specific gene mutation.
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USC researchers zoom into human genome with mammal DNA
USC researcher Dr Steven Gazal and his team have identified human genome base pairs that have remained constant over millions of years of mammalian evolution. These base pairs are linked to human disease. Using DNA from 240 mammal species, they identified genetic variations affecting an individual's survival and reproduction.
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CRISPR and single-cell sequencing highlight genetic variants for traits and diseases
This article highlights a new approach to address human genetics, using STING-seq which provides roadmap to identify variants and genes, enabling deeper understanding of the noncoding genome and targets for therapies
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Chances of eliminating HIV infection increased by dual gene-editing method
US researchers suggest that combing a dual gene-editing approach with antiretroviral drugs can eliminate HIV infections in animal models.
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Blocking a microRNA may prevent age-related conditions
Conditions like chronic inflammation, muscle loss and bone loss have an elevated microRNA, US researchers attempted to block this in aged mice.
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Genetics behind facial and skull changes in Down Syndrome mouse model
Progress in identifying the gene responsible for facial and skull changes in mouse model of Down Syndrome, made by UK researchers.
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Novel tool helps differentiate between cancerous and healthy cells for AML
Spanish scientists have developed a new method to identify between cancerous and healthy cells for cases of acute myeloid leukaemia (AML).