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Step forward in gene therapy to treat cause of sudden cardiac arrest
Using gene therapy, the researchers corrected abnormal heart rhythms by restoring a protein that heart cells need to establish connections with one another.
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Genetic Analysis
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Urine gene test has potential to predict bladder cancer earlier than ever
New urine gene test presented at EAU identified mutations across 10 genes, that were able to predict bladder cancer.
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Researchers find ancient virus genome drives autism
The scientists revealed in mice models that endogenous retrovirus activation increases a foetus’s susceptibility to autism.
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Usher syndrome: first nonhuman primate model
US researchers evaluate an experimental gene therapy in the first ever nonhuman primate model for Usher Syndrome.
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What is the link between serotonin and heart valve disease?
US researchers found that serotonin impacts the mitral valve in the heart which can lead to heart valve disease.
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New system for safer CRISPR-based gene drive testing and development
US researchers outline the development of a new system for testing and developing CRISPR-based gene drives in the laboratory, and safely converting them into tools for potential real-world applications.
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A change in genetic code causes lung cancer to develop
Using lung basal cell organoids, researchers identify a gene that directs the development of lung cancer and offers a better understanding of its disease treatment.
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Study identifies gene and proteins that could treat dry eye disease
Researchers found that proteins made by stem cells that regenerate the cornea could be new targets for treating dry eye disease.
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New method precisely locates gene activity and proteins across tissues
The scientists argue the technique enables the creation of complex, data-rich “maps” of organs, including diseased organs and tumours, which could be widely useful in pre-clinical research.
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Spatial lung cell atlas offers insights into disease and immune function
Researchers have genetically profiled nearly 200,000 cells from lungs, mapping their precise locations in tissue to discover an unexpected new immune niche in our airways.
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Scientists investigate the multi-omic landscape of NAFLD-to-NASH progression
Researchers have presented comprehensive multi-omic profiles to identify genes, non-coding RNAs, proteins, and plasma metabolites involved in NAFLD-to-NASH progression.
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Pattern of gene activity for ADHD is unlocked
US researchers identified that those with ADHD have differences in gene activity in the brain.
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Researchers develop and test risk score for pSSNS
Scientists have generated polygenic risk scores for developing paediatric steroid sensitive nephrotic syndrome (pSSNS), a kidney disease in children.
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New control system created for synthetic genes
MIT researchers have developed a technique that could help the production of monoclonal antibodies and other useful proteins.
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Study offers new insights into genetic mutations in ASD
The study’s findings have important implications for better understanding the neurological basis for ASD and developing effective therapies for patients.
