news
Neonatal ketone body determines premature ovarian ageing
The researchers found that ketone body deficiency in neonatal mice resulted in smaller ovarian follicle reservoir because of the increased apoptosis of primordial follicles.
List view / Grid view
Genetic Analysis
news
Genomic studies could impact pneumococcal disease vaccine design
A recent genomic surveillance study has demonstrated the value of genomics to inform vaccine design and highlight the challenge posted by shapeshifting bacteria.
news
Gene Lx9c11 helps mice survive virus infections
Researchers have discovered that “jumping gene” Lx9c11 has a profound effect on the immune system to virus infection.
news
Researchers find that CRISPR gene editing can give rise to cell toxicity and genomic instability
Using computational methods, researchers analysed the most popular CRISPR library designed for human cells and found 3,300 targeted spots that show strong toxic effects.
news
Novel insights into the genetic and molecular machinery that causes Alzheimer’s disease
Researchers have gained a clearer understanding of the genetic and molecular machinery in human microglia, findings that may provide insight into Alzheimer’s diseases development.
podcasts
Episode 11 – CRISPR with Dr Jakob Haaber, SNIPR Biome & Dr Richard Fox, Infinome Biosciences
Join leading experts as they discuss the wide range of uses for CRISPR, including for therapeutics and biomanufacturing.
news
Study reveals potential therapeutic targets for pancreatic cancer
Researchers analysed the expression of long non-coding RNAs in samples from patients and tumour cell lines, identifying a group of genes with augmented expression in pancreatic cancer.
news
First report from the world’s largest whole genome sequencing effort
Scientists have published a report on the whole genome sequences of 150 thousand participants in the UK biobank.
news
New discovery in cancer progression paves way to combat the disease
Researchers have identified an important gene that could enable more targeted treatment for cancer.
news
Scientists map networks of disease-associated immune genes
The new immune gene networks have implications for developing immunotherapies and understanding autoimmune diseases.
news
Visualising mRNA molecules in the brains of living mice
Scientists have developed a new imaging technique that allows researchers to see gene expression and mRNA molecules in the brains of live mice in real time.
article
Whole genome sequencing in cancer research
A recent whole genome sequencing study has revealed hidden insights into the causes of cancer. In an exclusive article, Dr Andrea Degasperi from the Early Cancer Institute at the University of Cambridge, UK spoke to Drug Target Review's Ria Kakkad about the study's implications and the future of whole genome sequencing.
news
Dysfunctional gene leads to potentially treatable deafness
Researchers have found that inherited mutations in the MINAR2 gene causes deafness. The findings suggest that deafness could be treated with genetic therapies.
news
New insights into how genetic factors affect body’s immune response in type 1 diabetes
The new study highlights 11 genes which could be considered as potential candidates for novel therapeutics for type 1 diabetes.
news
Target protein for diabetes drug linked to reduce the risk of Alzheimer’s disease
Scientists from Karolinska Institutet have found mechanisms associated with a particular diabetes drug that can also help to protect against Alzheimer’s disease.
