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No-cut CRISPR could be used to treat muscular dystrophy
Researchers have successfully used a no-cut CRISPR gene editing technique as a therapy for muscular dystrophy in mice models.
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Genome Editing
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Novel nanoparticles improve CRISPR gene editing
A study has used new synthetic lipids to deliver CRISPR gene editing tools into cells with up to 90 percent efficiency.
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RNA editing capabilities expanded with new CRISPR platform
A research team have developed a new CRISPR platform called RESCUE (RNA Editing for Specific C to U Exchange).
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CRISPR-Cas9 gene editing imaged for first time
Researchers have generated images of CRISPR-Cas9 gene editing for the first time, enabling improvement of the technique.
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Researchers develop directed evolution technique
New method for directed evolution could improve gene therapies and generic drug development.
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Potential cure for HIV revealed through combined therapies
A new study has used combined therapies to eliminate HIV from mice models, providing potential future cures.
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Longest successful gene expression raises hopes for gene editing therapies
A study has reported that genes delivered to rhesus monkeys are still being expressed four years later.
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Experimental treatment for sickle cell disease success
Researchers announce positive pre-clinical results for two sickle cell disease treatment strategies.
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New technology provides process for precise gene editing
Researchers have presented their new technology for accurately inserting genes into the genome without cutting DNA.
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CRISPR/Cas9-engineered cancer models: the next step forward for targeted cancer therapy
The advent of CRISPR/Cas9 gene editing, together with the plummeting cost of whole-genome sequencing, has cleared a path for the development of customised cancer cell models. Here, we discuss recent developments in the field and challenges associated with targeted-therapy resistance.
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‘CRISPR babies’ may have shorter life expectancy
A study of almost half a million people links a mutation that protects against HIV infection to an earlier death.
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Gene editing tools market valued at $258 million in 2018
The global gene editing tools market is estimated to have accounted for more than US$258 million in terms of value in 2018.
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Cancer-killing combination therapies unveiled with new drug-screening tool
Method IDs which target therapies, inadequately on their own, can be paired up to kill non-responsive cancers...
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New DNA ‘shredder’ technique goes beyond CRISPR’s scissors
A new CRISPR-based tool that acts more like a shredder is able to wipe out long stretches of DNA in human cells with programmable targeting...
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Gene therapy to reduce deafness in mice
Gene therapy has been used to restore hearing in an adult mouse model of DFNB9 deafness, one of the most frequent cases of congenital genetic deafness...
