news WHO and Switzerland launch BioHub for pathogen storage and analysis 25 May 2021 | By Victoria Rees (Drug Target Review) The WHO and Swiss Confederation are set to launch a BioHub Facility, intended to facilitate the sharing of pathogens globally.
news Genomic analysis reveals cellular cause of type 1 diabetes 20 May 2021 | By Victoria Rees (Drug Target Review) Combining two genomic methodologies, researchers have shown that pancreatic exocrine cells are implicated in type 1 diabetes.
news Novel CRISPR strategy developed for Duchenne muscular dystrophy 12 May 2021 | By Victoria Rees (Drug Target Review) A CRISPR gene editing technique has been developed to restore dystrophin, which is missing in many Duchenne muscular dystrophy (DMD) patients.
news Structure of DNA actively involved in genome regulation, study shows 10 May 2021 | By Victoria Rees (Drug Target Review) Researchers have shown that topoisomerase TOP2A eliminates negative supercoiling, causing an increase in the number of turns of DNA strands and impacting gene expression.
news Genetic profile of skeleton osteocytes mapped for first time 6 May 2021 | By Victoria Rees (Drug Target Review) Researchers have revealed which genes are switched on or off in osteocytes, a bone cell found in the skeleton.
news Team identifies paediatric acute myeloid leukaemia drug target 6 May 2021 | By Victoria Rees (Drug Target Review) Researchers have found that the gene mesothelin can be targeted by new antibody-drug conjugates to treat acute myeloid leukaemia in children.
news Gene therapy in Alzheimer’s mouse model preserves learning and memory 5 May 2021 | By Victoria Rees (Drug Target Review) A new gene therapy that introduced SynCav1 to the brains of Alzheimer's mouse models was shown to preserve neuronal and synaptic plasticity.
news CRISPR reveals genes involved in zebrafish spinal cord regeneration 3 May 2021 | By Victoria Rees (Drug Target Review) A CRISPR-Cas9 method has been used to identify which genes play a role in repairing zebrafish spinal cord injuries.
news UK Government to fund £37 million into genomics projects 30 April 2021 | By Victoria Rees (Drug Target Review) UK Health Secretary Matt Hancock has announced £37 million of funding for genomics and data projects to support the life sciences sector.
news Gene changes caused by Spike protein could explain long COVID 29 April 2021 | By Victoria Rees (Drug Target Review) Scientists have shown that the SARS-CoV-2 Spike protein can initiate gene expression changes, potentially explaining long COVID symptoms.
news First comprehensive single-cell atlas of human teeth compiled 28 April 2021 | By Victoria Rees (Drug Target Review) Using single-cell sequencing technology, researchers have gained insight into the interactions of dental pulp and periodontal cells of teeth.
news Study points to treatment approaches for advanced small-cell lung cancer 27 April 2021 | By Victoria Rees (Drug Target Review) Having sequenced samples of advanced small-cell lung cancer, researchers have identified patterns linked to resistance to certain therapies.
news Scientists call for awareness of unintended mutations from CRISPR 26 April 2021 | By Victoria Rees (Drug Target Review) Scientists have said that researchers need to be more aware of unintended mutations to human embryos following CRISPR-Cas9 genome editing.
news Scientists develop new CRISPR-based tool to control epigenome 19 April 2021 | By Victoria Rees (Drug Target Review) Researchers have used CRISPR to create a new technology that can switch off almost any gene in cells, called CRISPRoff.
news New gene therapy could preserve vision in retinitis pigmentosa patients 14 April 2021 | By Victoria Rees (Drug Target Review) Delivering Txnip to mice with retinitis pigmentosa was an effective treatment, making this approach a potential gene therapy for the disease.
