Age may be a primary determinant of melanoma treatment resistance
Scientists have shown that age may cause genetically identical melanoma skin cancer cells to respond differently to treatment, making age a primary factor in treatment response.
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Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
Scientists have shown that age may cause genetically identical melanoma skin cancer cells to respond differently to treatment, making age a primary factor in treatment response.
The Automated Recommendation Tool (ART) uses machine learning to accelerate the development of cells for specified goals, eg, bioprocessing and bioproduction.
In a new study, scientists identify some of the pitfalls when using CRISPR Cas9 to correct mutations in human embryos, such as the destruction of whole chromosomes.
New research reveals that age-related declines in cellular function and proliferation occur in multiple stages, accompanied by different inflammatory responses.
By targeting the mutated KRAS gene, researchers have developed an experimental vaccine that protected mice against a range of cancers.
Researchers reveal that SARS-CoV-2 is more infectious than SARS-CoV because it can use both ACE2 and neuropilin-1 to infect cells.
Topical delivery of a small interfering RNA (siRNA) using an ionic liquid complex significantly reduced levels of inflammatory cytokines and symptoms of psoriasis.
Hannah Balfour explores how genetic variation in G-protein-coupled receptors (GPCRs) and the proteins that regulate the duration of G protein signalling could be contributing to disease and people’s divergent responses to the same therapeutics.
A team has identified 219 molecules and genes that influence the severity of COVID-19 in patients, providing information that could aid the development of therapeutics.
Emmanuelle Charpentier and Jennifer Doudna have been given the 2020 Nobel Prize in Chemistry for their discovery and development of CRISPR-Cas9 genome editing.
Using CRISPR to cut out fusion genes, scientists were able to specifically induce cancer cell death in murine models of sarcoma and leukaemia.
New findings suggest that late-onset Alzheimer's Disease (AD) is driven by epigenetic changes in the brain.
Researchers have used heat to develop a new way to bioengineer cells that grow a certain way and bioprint 3D tissues.
A new study has shown that the mutated FBXO31 and RHOB genes can each alone cause cerebral palsy, offering potential drug targets.
Researchers used CRISPR gene-editing to develop a vaccine able to protect against the spread of the Leishmania major parasite which causes cutaneous leishmaniasis.