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Researchers explain how lymphoma cells metastasise to the brain
Chronic inflammatory processes in ageing brains lead to lymphoma cells that have entered the brain tissue being retained.
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Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
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Genomic medicine: cracking genomes to cure ‘incurable’ diseases
We are on the precipice of realising the true potential of genomics studies. Following completion of the Human Genome Project six years ago, huge strides have been made in understanding how the genome works, shedding light on disease pathogenesis and forging therapeutic efforts. In this article, Pushpanathan Muthuirulan explains how…
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Protein vital for enterovirus replication identified by study
Researchers have discovered a particular protein that is required for enterovirus replication and survival, presenting a therapeutic target.
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Expert view: Bio-Rad’s comprehensive genomics portfolio provides answers for every problem
Over three decades, Bio-Rad has built a broad genomics portfolio that touches on nearly every area of life science.
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Researchers improve CRISPR-Cas9 delivery efficiency
A team has used a lentiviral capsid-based bionanoparticle system to deliver CRISPR-Cas9 gene editing therapies, reducing undesired effects.
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Largest genome sequencing project launched in UK
The UK Biobank, the world’s largest genetics project, will sequence 500,000 genetic samples, which will be available to researchers everywhere.
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New gene therapy repairs neuron stroke damage in mice
Researchers have developed a new treatment method which turned glial cells into functioning neurons in mice after stroke.
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Nervous system discovery overturns previous theory
A ground-breaking nervous system discovery could be significant for the treatment of different neurological diseases.
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Genomics In-Depth Focus 2019
In this In-Depth Focus are articles on how genomics could revolutionise clinical treatment and an insight into the promise and pitfalls of using CRISPR.
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Drug Target Review – Issue 3 2019
This issue includes an investigation into utilising recombinant antibodies for research, a highlight on protein design using computational methods and an examination of the advances in genomic medicine. Also in the issue are articles on next generation sequencing and upstream bioprocessing.
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Researchers develop new DNA microscopy technique
The novel method for imaging molecules in cells and tissue samples, called DNA microscopy, could improve knowledge of disease development.
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Medical Research Council updates brain tissue database
The UK Brain Banks Network has been enhanced to include genomic data, which can be accessed by researchers worldwide.
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Researchers identify pancreatic cancer protein drug target
A protein that causes pancreatic ductal adenocarcinoma has been identified as a therapeutic target by researchers.
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Uncharted area of genome mapped by advanced imaging
Researchers have mapped a previously uncharted region of the human genome which could lead to tests for certain conditions in the future.
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ALS pathological mediator identified by researchers
A potential target for ALS has been revealed by a study which found the Fos-B gene encouraged axonal branching.
