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Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
Individualised therapies that target the specific genetic features of tumours have the potential to transform cancer diagnosis, treatment and care. However, several challenges remain before these approaches can be widely used in the clinic.
Next generation sequencing (NGS) has revolutionised genomics research providing a wealth of genetic information of immense value to researchers. NGS technologies have been evolving over the last decade, leading to substantial improvement in understanding different biological systems from broader and deeper perspectives.1
6 September 2018 | By Takara Bio
The data presented in this application note demonstrates how SMARTer ICELL8 Single-Cell System can be used to generate high-quality RNA-seq libraries that provide full-length transcript sequence information from hundreds of single cells in parallel...
Assessing targets that are unable – or rather, extremely difficult – to reach pharmacologically, has prevented researchers from achieving desired clinical successes, most notably in the realm of cancer research. However, many advances are being made to shedlight on these difficult yet desirable target areas.
Researchers have developed a new CHAOS method to combat antibiotic resistance, using CRISPR DNA modification techniques...
Despite the human genome being first sequenced almost 20 years ago, researchers know comparatively little about how the genome is organised within cells. But a new TSA-Seq technique is changing that.
Researchers have determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation...
Researchers have adapted CRISPR to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building...
Researchers have identified a gene that when inhibited, reduced human non-small cell lung cancer tumours from growing...
Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells...
Scientists have identified an easy upgrade for the technology that would lead to more accurate gene editing...
A specific haplotype was identified as having the highest risk of development, with another showing the lowest risk...
A new gene associated with disease severity in models of rheumatoid arthritis has been identified by...
Blindness in children has been linked to a recessive genetic disorder caused by the MARK3 gene...
