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Sequencing offers clues to progression toward multiple myeloma
Researchers have carried out the largest genomic analysis of patients with SMM to explain the biology of the disease and how it unfolds through time...
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Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
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Leukaemia protective role of Y chromosome gene discovered
Scientists have discovered the first leukaemia protective gene that is specific to the male-only Y chromosome...
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Genomic analysis unravels complexities of the most common form of lymphoma
Genomic analysis has shown a better framework for understanding lymphoma’s many forms and will help to predict individual patient outcomes and guide personalised treatment.
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FoxM1 gene provides promising target for pulmonary hypertension
The FoxM1 gene will drive the development of new drugs to reverse a process called vascular remodelling - a key feature in pulmonary hypertension...
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Genetic catalyst identifies the evolution of antibiotic resistance
Researchers have shown that it is possible to identify genetic catalysts that accelerate the evolution of antibiotic resistance in bacteria...
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The role of ‘extra’ DNA in cancer evolution and therapy resistance
A team of scientists have reported that tumour progression was often driven by cancer-promoting genes, known as oncogenes, on extrachromosomal pieces of DNA.
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Scientists generate an atlas of the human genome using stem cells
Scientists have generated an atlas of the human genome using a state-of-the-art gene editing technology and human embryonic stem cells, illuminating the roles that our genes play in health and disease.
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Chemogenetics provides hope for severe epilepsy
Researchers believe that they have found a method that in the future could help people suffering from epilepsy so severe that all current treatment is ineffective...
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Study reveals every bowel tumour and bowel cancer cell have unique genetic fingerprints
Single-cell technology and organoids enable researchers to study cancer-specific processes...
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Application note: CRISPR/Cas9 genome-edited cells express nanoBRET-donor that monitors protein interaction and trafficking
In this application note, BMG Labtech discuss how the Bioluminescence resonance energy transfer (BRET) is a versatile tool to study interactions and trafficking in proteins.
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KLF14 gene may increase risk of type 2 diabetes
Scientists have identified a gene that in women is linked to the creation and location of new fat cells and therefore is thought to contribute to the risk of type 2 diabetes...
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FGF21 gene variant found to lower body fat
Researchers have found that a gene that makes humans eat more sugar can also lower body fat...
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BNIP1 identified as a risk gene for ALS
Broad data analysis points to genetic similarities between Lou Gehrig's Disease and a form of dementia...
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How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
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An advance for precision medicine
Discovery allows scientists to index thousands of cells simultaneously, a 40-fold increase from the current method...