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The role of ‘extra’ DNA in cancer evolution and therapy resistance
A team of scientists have reported that tumour progression was often driven by cancer-promoting genes, known as oncogenes, on extrachromosomal pieces of DNA.
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Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
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Scientists generate an atlas of the human genome using stem cells
Scientists have generated an atlas of the human genome using a state-of-the-art gene editing technology and human embryonic stem cells, illuminating the roles that our genes play in health and disease.
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Chemogenetics provides hope for severe epilepsy
Researchers believe that they have found a method that in the future could help people suffering from epilepsy so severe that all current treatment is ineffective...
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Study reveals every bowel tumour and bowel cancer cell have unique genetic fingerprints
Single-cell technology and organoids enable researchers to study cancer-specific processes...
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Application note: CRISPR/Cas9 genome-edited cells express nanoBRET-donor that monitors protein interaction and trafficking
In this application note, BMG Labtech discuss how the Bioluminescence resonance energy transfer (BRET) is a versatile tool to study interactions and trafficking in proteins.
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KLF14 gene may increase risk of type 2 diabetes
Scientists have identified a gene that in women is linked to the creation and location of new fat cells and therefore is thought to contribute to the risk of type 2 diabetes...
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FGF21 gene variant found to lower body fat
Researchers have found that a gene that makes humans eat more sugar can also lower body fat...
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BNIP1 identified as a risk gene for ALS
Broad data analysis points to genetic similarities between Lou Gehrig's Disease and a form of dementia...
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How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
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An advance for precision medicine
Discovery allows scientists to index thousands of cells simultaneously, a 40-fold increase from the current method...
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Genes can help predict children’s risk of type 1 diabetes
A type 1 diabetes genetic score can identify infants at risk for pre-symptomatic type 1 diabetes...
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Astrocytes may help brain heal from stroke and spinal cord injuries
Scientists have found a genetic trigger that may improve the brain's ability to heal from a range of debilitating conditions...
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Lancet tool enables accurate identification of rare mutations in cancer cells
A new computational method allows scientists to identify rare gene mutations in cancer cells with greater accuracy and sensitivity...
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KIF5A gene associated with the development of ALS
An international team of researchers has identified a new gene associated with the development of amyotrophic lateral sclerosis...
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Scientists identify genes that could develop therapies for EBV-related cancers
Researchers have identified two genes that are responsible for governing the replication of the Epstein-Barr virus, an infection that drives the growth of several types of cancer...
