news The role of ‘extra’ DNA in cancer evolution and therapy resistance 26 April 2018 | By Drug Target Review A team of scientists have reported that tumour progression was often driven by cancer-promoting genes, known as oncogenes, on extrachromosomal pieces of DNA.
news Scientists generate an atlas of the human genome using stem cells 25 April 2018 | By Drug Target Review Scientists have generated an atlas of the human genome using a state-of-the-art gene editing technology and human embryonic stem cells, illuminating the roles that our genes play in health and disease.
news Chemogenetics provides hope for severe epilepsy 18 April 2018 | By Drug Target Review Researchers believe that they have found a method that in the future could help people suffering from epilepsy so severe that all current treatment is ineffective...
news Study reveals every bowel tumour and bowel cancer cell have unique genetic fingerprints 13 April 2018 | By Drug Target Review Single-cell technology and organoids enable researchers to study cancer-specific processes...
whitepaper Application note: CRISPR/Cas9 genome-edited cells express nanoBRET-donor that monitors protein interaction and trafficking 12 April 2018 | By BMG Labtech GmbH, Carl White (Molecular Endocrinology and Pharmacology), Ethan See (The University of Western Australia), Kevin Pfleger (Dimerix Limited) In this application note, BMG Labtech discuss how the Bioluminescence resonance energy transfer (BRET) is a versatile tool to study interactions and trafficking in proteins.
news KLF14 gene may increase risk of type 2 diabetes 12 April 2018 | By Drug Target Review Scientists have identified a gene that in women is linked to the creation and location of new fat cells and therefore is thought to contribute to the risk of type 2 diabetes...
news FGF21 gene variant found to lower body fat 11 April 2018 | By Drug Target Review Researchers have found that a gene that makes humans eat more sugar can also lower body fat...
news BNIP1 identified as a risk gene for ALS 10 April 2018 | By Dr Zara Kassam (Drug Target Review) Broad data analysis points to genetic similarities between Lou Gehrig's Disease and a form of dementia...
article How the study of lipidomics is benefiting from recent advances in mass spectrometry 10 April 2018 | By Cristina Legido-Quigley (Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen) There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
news An advance for precision medicine 10 April 2018 | By Drug Target Review Discovery allows scientists to index thousands of cells simultaneously, a 40-fold increase from the current method...
news Genes can help predict children’s risk of type 1 diabetes 4 April 2018 | By Drug Target Review A type 1 diabetes genetic score can identify infants at risk for pre-symptomatic type 1 diabetes...
news Astrocytes may help brain heal from stroke and spinal cord injuries 30 March 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have found a genetic trigger that may improve the brain's ability to heal from a range of debilitating conditions...
news Lancet tool enables accurate identification of rare mutations in cancer cells 26 March 2018 | By Dr Zara Kassam (Drug Target Review) A new computational method allows scientists to identify rare gene mutations in cancer cells with greater accuracy and sensitivity...
news KIF5A gene associated with the development of ALS 26 March 2018 | By Dr Zara Kassam (Drug Target Review) An international team of researchers has identified a new gene associated with the development of amyotrophic lateral sclerosis...
news Scientists identify genes that could develop therapies for EBV-related cancers 22 March 2018 | By Drug Target Review Researchers have identified two genes that are responsible for governing the replication of the Epstein-Barr virus, an infection that drives the growth of several types of cancer...
