news
BRCA1 methylation associated with risk for high-grade ovarian cancer
Normal tissue BRCA1 methylation is associated with risk for high-grade ovarian cancer and may occur as a prenatal event...
List view / Grid view
Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
news
Autism risk factor search aided by epigenetics study
Scientists have identified more than 2,000 regulatory regions involved in learning that correlate strongly with autism, suggesting future focus for autism research.
news
MAFA gene provides insight into the genomics of diabetes
Scientists have uncovered insights into the genomics of diabetes through the rare case of a family where one gene is associated with two opposing conditions...
news
Mitochondrial disease can be inherited from healthy parents
Researchers have shown for the first time how children can inherit a severe -- potentially fatal - mitochondrial disease from a healthy mother...
news
Super-silenced DNA study hints at new ways to reprogram cells
Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity.
news
X chromosome reactivation could treat Rett syndrome
Reactivation of the inactive X chromosome could lead to an increased expression of the healthy protein underlying the neurodevelopmental disorder...
news
Brainstem changes identified in Parkinson’s disease
Researchers have found that patients with Parkinson's disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death...
news
Chemical oscillators offer a new level of molecular control
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit computation within molecular systems...
article
Proteogenomics research – on the frontier of precision medicine
Proteogenomics is the systematic and comprehensive integration of proteomics with genomics and transcriptomics. Proteogenomics is opening new hallmarks in biomedical research. Recently, several studies have demonstrated the relevance of proteogenomics in cancer research. This article provides a brief review of the advantages of proteogenomics in precision medicine.
news
Using 3D cell cultures to fight anti-cancer therapy resistance
An international team of researchers have developed 3D cell cultures in which genes can be specifically modified to improve the use of targeted anti-cancer drugs...
article
Patient-derived neural progenitor cells as a drug discovery model for mitochondrial diseases
Mitochondrial DNA (mtDNA) mutations cause severe disorders that are untreatable and mostly affect the nervous system. The difficulty in funding therapies may also be explained by the lack of viable modelling systems...
whitepaper
Application note: KingFisher sample purification system
Next generation sequencing sample preparation on the KingFisher platform...
news
Pancreatic cancer: specific protein promotes development of pancreatitis and tumours
A study has shown that disruption to cell autophagy is involved in the development of pancreatic cancer.
news
GDF6 gene associated with metastatic melanoma
Researchers have revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma...
