news
Cell contacts in embryonic development determine cellular fate
Researchers have identified a positive feedback loop between the duration of cell-cell contacts and the specification of a cell's fate...
List view / Grid view
Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
news
Stem cell line offers expanded potential for research and treatments
Researchers have created Expanded Potential Stem Cells that have greater potential for embryonic development than current stem cell lines...
news
Underlying genetic causes of congenital heart disease identified
Researchers have helped shed light on some of the underlying genetic causes of CHD as well as the long-term outlook for patients who carry these mutations...
news
Microcapsules to enhance the efficiency of genome-editing
Researchers have found that polymer and hybrid silica-coated microcapsules are efficient in genome-editing...
news
CRISPR-engineered cancer model to test therapeutics
A new technique for modelling leukaemia may aid drug discovery...
news
CRISPR-Cas9 used to systematically inactivate genes in colorectal cancer
Researchers have used CRISPR-Cas9 to inactivate genes in human colorectal cancer cell lines -- one with normal KRAS gene and one with a mutant KRAS...
news
MMP20 gene variants linked to high-risk childhood cancers
Paediatric researchers have identified common gene variants that raise the risk of an aggressive forms of childhood cancer...
news
Genome editing reveals a role for OCT4 in human embryogenesis
Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development...
news
GREB1L mutations associated with renal agenesis
A team of researchers has identified the mutated gene GREB1L is linked to renal agenesis...
news
KDM4 inhibitor brings new hope for breast cancer
Scientists have shown that inhibiting the epigenetic regulator KDM4 may offer a potential novel treatment for breast cancer...
news
New genetic cause discovered for photosensitive blood disorder
Researchers have uncovered a new genetic cause for erythropoietic protoporphyria...
news
Novel genetic mutation discovered in Parkinson’s disease
Researchers have identified the first case of a patient with Parkinson's disease carrying a mutation in the ACMSD gene...
article
How next-generation sequencing is opening the door for drug discovery
The Wellcome Trust Sanger Institute's Kim Judge explains how Next Generation Sequencing forms a crucial part of the scientist’s toolkit and makes a valuable contribution to the field of drug discovery...
article
Calcilytics as potential novel therapeutic treatments to halt Alzheimer’s disease
Alzheimer’s disease (AD) is the most prevalent form of dementia.1 The common (>95% of cases) slow-developing form of the ailment is known as late-onset AD (LOAD) or sporadic AD (SAD). The rare (
news
Genetic testing leads to response in MET fusion lung cancer
Researchers have identified a rare fusion involving the gene MET leading researchers to treat the cancer with a targeted therapy...