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Genomics

Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.

news

Computational analysis reveals novel cancer genes

31 October 2017 | By Dr Zara Kassam (Drug Target Review)

Statistical model pinpoints 27 novel genes thought to prevent cancer from forming...

news

CRISPR engineered to edit single RNA letters

26 October 2017 | By Dr Zara Kassam (Drug Target Review)

New 'REPAIR' system edits RNA, rather than DNA, without permanently affecting the genome...

news

Alpha-1 antitrypsin deficiency shows promise in rare liver disease

20 October 2017 | By Dr Zara Kassam (Drug Target Review)

Nuclease-free gene editing has been found to correct mutated cells ...

news

Gene transcription in CD8 T cells differentiates chronic from resolving HCV

17 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with HCV...

news

Modified CRISPR technique used to combat Parkinson’s disease

13 October 2017 | By Dr Zara Kassam (Drug Target Review)

Biological engineers identify genes that protect against protein linked to Parkinson's disease...

news

Cell contacts in embryonic development determine cellular fate

12 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a positive feedback loop between the duration of cell-cell contacts and the specification of a cell's fate...

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Stem cell line offers expanded potential for research and treatments

11 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have created Expanded Potential Stem Cells that have greater potential for embryonic development than current stem cell lines...

news

Underlying genetic causes of congenital heart disease identified

9 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have helped shed light on some of the underlying genetic causes of CHD as well as the long-term outlook for patients who carry these mutations...

news

Microcapsules to enhance the efficiency of genome-editing

6 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have found that polymer and hybrid silica-coated microcapsules are efficient in genome-editing...

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CRISPR-engineered cancer model to test therapeutics

5 October 2017 | By Dr Zara Kassam (Drug Target Review)

A new technique for modelling leukaemia may aid drug discovery...

news

CRISPR-Cas9 used to systematically inactivate genes in colorectal cancer

28 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used CRISPR-Cas9 to inactivate genes in human colorectal cancer cell lines -- one with normal KRAS gene and one with a mutant KRAS...

news

MMP20 gene variants linked to high-risk childhood cancers

26 September 2017 | By Dr Zara Kassam (Drug Target Review)

Paediatric researchers have identified common gene variants that raise the risk of an aggressive forms of childhood cancer...

news

Genome editing reveals a role for OCT4 in human embryogenesis

21 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development...

news

GREB1L mutations associated with renal agenesis

19 September 2017 | By Dr Zara Kassam (Drug Target Review)

A team of researchers has identified the mutated gene GREB1L is linked to renal agenesis...

news

KDM4 inhibitor brings new hope for breast cancer

15 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have shown that inhibiting the epigenetic regulator KDM4 may offer a potential novel treatment for breast cancer...

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Genomics