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Potential new treatment for Fragile X targets one gene to affect many
Inhibitors of chromatin remodelling proteins may be a potential treatment for Fragile X Syndrome...
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Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
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Sonic Hedgehog pathway identified as a target against medulloblastoma
Researchers raise hopes for developing a combination targeted therapy to treat medulloblastoma and other tumours...
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Prenatal exposure to BPA at low levels can affect gene expression
Prenatal exposure to BPA affects gene expression related to sexual differentiation and neurodevelopment in the developing brain...
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Computational analysis reveals novel cancer genes
Statistical model pinpoints 27 novel genes thought to prevent cancer from forming...
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CRISPR engineered to edit single RNA letters
New 'REPAIR' system edits RNA, rather than DNA, without permanently affecting the genome...
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Alpha-1 antitrypsin deficiency shows promise in rare liver disease
Nuclease-free gene editing has been found to correct mutated cells ...
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Gene transcription in CD8 T cells differentiates chronic from resolving HCV
Researchers have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with HCV...
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Modified CRISPR technique used to combat Parkinson’s disease
Biological engineers identify genes that protect against protein linked to Parkinson's disease...
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Cell contacts in embryonic development determine cellular fate
Researchers have identified a positive feedback loop between the duration of cell-cell contacts and the specification of a cell's fate...
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Stem cell line offers expanded potential for research and treatments
Researchers have created Expanded Potential Stem Cells that have greater potential for embryonic development than current stem cell lines...
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Underlying genetic causes of congenital heart disease identified
Researchers have helped shed light on some of the underlying genetic causes of CHD as well as the long-term outlook for patients who carry these mutations...
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Microcapsules to enhance the efficiency of genome-editing
Researchers have found that polymer and hybrid silica-coated microcapsules are efficient in genome-editing...
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CRISPR-engineered cancer model to test therapeutics
A new technique for modelling leukaemia may aid drug discovery...
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CRISPR-Cas9 used to systematically inactivate genes in colorectal cancer
Researchers have used CRISPR-Cas9 to inactivate genes in human colorectal cancer cell lines -- one with normal KRAS gene and one with a mutant KRAS...
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MMP20 gene variants linked to high-risk childhood cancers
Paediatric researchers have identified common gene variants that raise the risk of an aggressive forms of childhood cancer...
