CRISPR-Cas9 used to systematically inactivate genes in colorectal cancer
Researchers have used CRISPR-Cas9 to inactivate genes in human colorectal cancer cell lines -- one with normal KRAS gene and one with a mutant KRAS...
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Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
Researchers have used CRISPR-Cas9 to inactivate genes in human colorectal cancer cell lines -- one with normal KRAS gene and one with a mutant KRAS...
Paediatric researchers have identified common gene variants that raise the risk of an aggressive forms of childhood cancer...
Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development...
A team of researchers has identified the mutated gene GREB1L is linked to renal agenesis...
Scientists have shown that inhibiting the epigenetic regulator KDM4 may offer a potential novel treatment for breast cancer...
Researchers have uncovered a new genetic cause for erythropoietic protoporphyria...
Researchers have identified the first case of a patient with Parkinson's disease carrying a mutation in the ACMSD gene...
The Wellcome Trust Sanger Institute's Kim Judge explains how Next Generation Sequencing forms a crucial part of the scientist’s toolkit and makes a valuable contribution to the field of drug discovery...
Alzheimer’s disease (AD) is the most prevalent form of dementia.1 The common (>95% of cases) slow-developing form of the ailment is known as late-onset AD (LOAD) or sporadic AD (SAD). The rare (
Researchers have identified a rare fusion involving the gene MET leading researchers to treat the cancer with a targeted therapy...
Study from NIH may help improve prenatal genetic screening...
A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...
Scientists have developed an innovative system to identify and characterise the molecular components that control the activities of regulatory DNA sequences...
Researchers have developed a test to diagnose a rare and severe immune defect...
Researchers have determined that a specific region of the duodenal-jejunal flexure, shows a high frequency of gastrointestinal stromal tumours with mutations of the NF1 gene...