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Breakthrough method yields trove of neuronal subtypes and gene regulators
Researchers have discovered a trove of neuronal subtypes and gene regulators, using a new method they developed called snmC-seq...
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Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
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NIH accelerates the use of genomics in clinical care
The National Institutes of Health is awarding $18.9 million towards research that aims to accelerate the use of genome sequencing in clinical care...
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CRISPR identifies essential genes for cancer immunotherapy
Researchers have used CRISPR to stop the expression of individual genes in cancer cells, by knocking out every known protein-encoding gene in the human genome...
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CRISPR-Cas9 repairs genetic mutation in human embryos
"Well thought through and brilliantly executed" study shows different DNA-repair mechanism in embryos compared to iPSCs
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Novel perspectives on anti-amyloid treatment for the prevention of Alzheimer’s
A collaboration between Prof Lucía Chávez-Gutiérrez and Prof Bart De Strooper of VIB-KU Leuven has revealed the molecular basis of the hereditary form of Alzheimer’s disease that strikes early in life.
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Researchers use CRISPR-Cas9 to target retinal angiogenesis.
Researchers have used CRISPR-Cas9 to target retinal angiogenesis via an adeno-associated virus to deliver genomic edits to target vascular endothelial cell growth factor...
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Researchers find new genes link to arthritis in bone marrow lesions
Researchers have found a pattern of genes which is characteristic of osteoarthritis and may be a step towards better treatments for this condition.
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Scientists discover new bacterial defence mechanism of CRISPR-Cas system
A team of researchers – headed by the University of Zurich – have discovered a new mechanism by which bacteria are protected from invading viruses and molecular parasites.
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Two new genes linked to Alzheimer’s risk
Researchers have identified two genes that influence a person’s risk of developing Alzheimer’s disease.
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Largest genome-wide study of lung cancer susceptibility conducted
A new study conducted by an international team of lung cancer researchers have identified new genetic variants for lung cancer risk.
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Ryboquin raises £1.8m for drug development in gene therapy
This latest funding round attracts two prominent new investors; Brian Kennedy and Sir Brian Souter.
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Study asks if mistaken antibodies led research down 20-year dead end
For nearly two decades researchers have sought a way to target an oestrogen receptor in the hope they could improve breast cancer survival, but an article contends that the effort may never pan out.
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Dynamic DNA helps ward off gene damage
MRC-funded researchers have identified properties in DNA’s protective structure that could transform the way scientists think about the human genome.
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Over one thousand new microbial genomes discovered
Scientists at the U.S Department of Energy Joint Genome Institute (DOE JGI) have published a report that references 1,003 phylogenetically diverse bacterial and archaeal reference genomes.
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Screening for genetic diseases & chromosomal defects with a single biopsy
Couples who are undergoing pre-implantation genetic diagnosis (PGD) in order to avoid transmission of inherited diseases, such as Duchenne muscular dystrophy or cystic fibrosis, should also have their embryos screened for abnormal numbers of chromosomes at the same time, say Italian researchers.
