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Genomics

Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.

news

Histone 1, the guardian of genome stability

18 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have explained for the first time that the suppression of histone 1 causes cell damage and genomic instability...

news

Two-step process leads to cell immortalisation and cancer

18 August 2017 | By Dr Zara Kassam (Drug Target Review)

New research, has studied the immortalisation process using genome-engineered cells...

news

New genetic analysis reveals early diagnosis for breast cancer

15 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have shown that catching and treating breast cancer before it spreads is now a realistic goal...

news

£2m collaboration to focus on gene and cell therapy

14 August 2017 | By Dr Zara Kassam (Drug Target Review)

A leading gene and cell therapy group has announced a collaboration focusing on gene and cell therapy manufacturing..

news

Improved analysis of kidney cancer

11 August 2017 | By Dr Zara Kassam (Drug Target Review)

A research team have discovered that in the Cancer Genome Atlas database the gene expression in reference samples differs from normal tissue, depending on where in the kidney the samples happen to have been taken from...

news

Breakthrough method yields trove of neuronal subtypes and gene regulators

11 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered a trove of neuronal subtypes and gene regulators, using a new method they developed called snmC-seq...

news

NIH accelerates the use of genomics in clinical care

9 August 2017 | By Dr Zara Kassam (Drug Target Review)

The National Institutes of Health is awarding $18.9 million towards research that aims to accelerate the use of genome sequencing in clinical care...

news

CRISPR identifies essential genes for cancer immunotherapy

8 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used CRISPR to stop the expression of individual genes in cancer cells, by knocking out every known protein-encoding gene in the human genome...

article

CRISPR-Cas9 repairs genetic mutation in human embryos

3 August 2017 | By James Adjaye (Institute for Stem Cell Research and Regenerative Medicine), Justin Bryans, Steve Bremer (Drug Target Review)

"Well thought through and brilliantly executed" study shows different DNA-repair mechanism in embryos compared to iPSCs

Novel perspectives on anti-amyloid treatment for the prevention of Alzheimer’s disease

news

Novel perspectives on anti-amyloid treatment for the prevention of Alzheimer’s

27 July 2017 | By Sarah Wills (Drug Target Review)

A collaboration between Prof Lucía Chávez-Gutiérrez and Prof Bart De Strooper of VIB-KU Leuven has revealed the molecular basis of the hereditary form of Alzheimer’s disease that strikes early in life.

news

Researchers use CRISPR-Cas9 to target retinal angiogenesis.

25 July 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used CRISPR-Cas9 to target retinal angiogenesis via an adeno-associated virus to deliver genomic edits to target vascular endothelial cell growth factor...

news

Researchers find new genes link to arthritis in bone marrow lesions

19 July 2017 | By Niamh Marriott (Drug Target Review)

Researchers have found a pattern of genes which is characteristic of osteoarthritis and may be a step towards better treatments for this condition.

news

Scientists discover new bacterial defence mechanism of CRISPR-Cas system

19 July 2017 | By Drug Target Review

A team of researchers – headed by the University of Zurich – have discovered a new mechanism by which bacteria are protected from invading viruses and molecular parasites.

Two new genes linked to Alzheimer's risk

news

Two new genes linked to Alzheimer’s risk

18 July 2017 | By Sarah Wills (Drug Target Review)

Researchers have identified two genes that influence a person’s risk of developing Alzheimer’s disease.

news

Largest genome-wide study of lung cancer susceptibility conducted

13 July 2017 | By Niamh Marriott (Drug Target Review)

A new study conducted by an international team of lung cancer researchers have identified new genetic variants for lung cancer risk.

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Genomics