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GIST tumours linked to NF1 mutations
Researchers have determined that a specific region of the duodenal-jejunal flexure, shows a high frequency of gastrointestinal stromal tumours with mutations of the NF1 gene...
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Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
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Histone 1, the guardian of genome stability
Researchers have explained for the first time that the suppression of histone 1 causes cell damage and genomic instability...
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Two-step process leads to cell immortalisation and cancer
New research, has studied the immortalisation process using genome-engineered cells...
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New genetic analysis reveals early diagnosis for breast cancer
Researchers have shown that catching and treating breast cancer before it spreads is now a realistic goal...
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£2m collaboration to focus on gene and cell therapy
A leading gene and cell therapy group has announced a collaboration focusing on gene and cell therapy manufacturing..
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Improved analysis of kidney cancer
A research team have discovered that in the Cancer Genome Atlas database the gene expression in reference samples differs from normal tissue, depending on where in the kidney the samples happen to have been taken from...
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Breakthrough method yields trove of neuronal subtypes and gene regulators
Researchers have discovered a trove of neuronal subtypes and gene regulators, using a new method they developed called snmC-seq...
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NIH accelerates the use of genomics in clinical care
The National Institutes of Health is awarding $18.9 million towards research that aims to accelerate the use of genome sequencing in clinical care...
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CRISPR identifies essential genes for cancer immunotherapy
Researchers have used CRISPR to stop the expression of individual genes in cancer cells, by knocking out every known protein-encoding gene in the human genome...
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CRISPR-Cas9 repairs genetic mutation in human embryos
"Well thought through and brilliantly executed" study shows different DNA-repair mechanism in embryos compared to iPSCs
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Novel perspectives on anti-amyloid treatment for the prevention of Alzheimer’s
A collaboration between Prof Lucía Chávez-Gutiérrez and Prof Bart De Strooper of VIB-KU Leuven has revealed the molecular basis of the hereditary form of Alzheimer’s disease that strikes early in life.
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Researchers use CRISPR-Cas9 to target retinal angiogenesis.
Researchers have used CRISPR-Cas9 to target retinal angiogenesis via an adeno-associated virus to deliver genomic edits to target vascular endothelial cell growth factor...
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Researchers find new genes link to arthritis in bone marrow lesions
Researchers have found a pattern of genes which is characteristic of osteoarthritis and may be a step towards better treatments for this condition.
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Scientists discover new bacterial defence mechanism of CRISPR-Cas system
A team of researchers – headed by the University of Zurich – have discovered a new mechanism by which bacteria are protected from invading viruses and molecular parasites.
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Two new genes linked to Alzheimer’s risk
Researchers have identified two genes that influence a person’s risk of developing Alzheimer’s disease.
