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The future for quality control of mRNA medications
Japanese researchers combine cutting edge mass spectrometry with software analysis to elucidate mRNA structure.
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Genomics
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
news
What do cancer cells crave?
US researchers uncover the amino acid: arginine, that prompts genetic mutations in cancer cells.
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What is the link between serotonin and heart valve disease?
US researchers found that serotonin impacts the mitral valve in the heart which can lead to heart valve disease.
webinar
Using integrative biophysical approaches to understand GPCR regulation by β-arrestins
30 January 2023 | By Thermo Fisher Scientific
Watch this webinar to learn how an integrated structural biology workflow can be used to get crucial structural insights on key protein targets that are of therapeutic interest.
news
Researchers develop novel method to insert large DNA sequences more accurately in cells
The scientists say that the engineered CRISPR enzymes could overcome key limitations for eventual use to treat genetic diseases irrespective of a patient’s particular mutation.
news
A change in genetic code causes lung cancer to develop
Using lung basal cell organoids, researchers identify a gene that directs the development of lung cancer and offers a better understanding of its disease treatment.
news
Study identifies gene and proteins that could treat dry eye disease
Researchers found that proteins made by stem cells that regenerate the cornea could be new targets for treating dry eye disease.
news
Humanised mouse model identifies the best match for organ donor
US researchers have developed a mouse model that holds promise in identifying the best organ donor and showing early signs of transplant rejection.
news
Novel protein coordinates melanin production
Japanese researchers reported that a key transcription factor “Nrf3” regulates the process of melanin production in mouse and human cells.
news
New method precisely locates gene activity and proteins across tissues
The scientists argue the technique enables the creation of complex, data-rich “maps” of organs, including diseased organs and tumours, which could be widely useful in pre-clinical research.
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Researchers generate organoid model for gastroesophageal junction cancer
The scientists discovered that dual knockout of genes in organoids grown from human tissue can generate a model of a potential therapeutic target for gastroesophageal junction cancer.
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Researchers have sculpted the human body plan in a dish
The scientists hope the human body plan will increase the understanding of the aetiology and pathology of disease.
news
Spatial lung cell atlas offers insights into disease and immune function
Researchers have genetically profiled nearly 200,000 cells from lungs, mapping their precise locations in tissue to discover an unexpected new immune niche in our airways.
article
RNA therapeutics: the key to treat rare disease?
This exclusive interview highlights some of Dr Arthur Suckow’s insights into how his team uses RNA therapies to treat rare diseases such as Charcot-Marie-Tooth 1A.
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Scientists investigate the multi-omic landscape of NAFLD-to-NASH progression
Researchers have presented comprehensive multi-omic profiles to identify genes, non-coding RNAs, proteins, and plasma metabolites involved in NAFLD-to-NASH progression.