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Genomics

Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.

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Researchers make progress towards CRISPR-based microbiome editing

9 November 2022 | By Izzy Wood (Drug Target Review)

US researchers have engineered bacteriophages to deliver CRISPR-Cas payloads for targeted editing of a bacterium.

child, a girl makes a shot to the toy bear, the insulin syringe

news

Scientists discover the cause of Congenital Hyperinsulinism

8 November 2022 | By Ria Kakkad (Drug Target Review)

A research team at the University of Exeter have found that the unexplored genomic control regions yield the key to finding causes of Congenital Hyperinsulinism.

Monkeypox virus cells outbreak medical banner. Monkeypox virus cells on white sciense background. Monkey pox microbiological vector background.

news

Monkeypox mutations cause virus to spread rapidly, evade drugs and vaccines

7 November 2022 | By Ria Kakkad (Drug Target Review)

Researchers show how monkeypox mutations cause virus to replicate, spread faster.

news

Pre-clinical model of appendiceal cancer developed

3 November 2022 | By Izzy Wood (Drug Target Review)

Researchers from the University of California have developed the first pre-clinical model of appendiceal cancer, containing all elements of the tumour.

Female doctor holding virtual Intestine in hand. Handrawn human organ, blurred photo, raw photo colors. Healthcare hospital service concept stock photo

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Researchers find that reduction in protein synthesis could lead to Feingold syndrome

2 November 2022 | By Ria Kakkad (Drug Target Review)

The researchers used a zebrafish model to test mutations in Mycn, a gene which causes Feingold syndrome.

Autism. Autism spectrum disorder(ASD). Autism word made out of playdough. Wooden background. Close up.

news

Study offers new insights into genetic mutations in ASD

2 November 2022 | By Ria Kakkad (Drug Target Review)

The study’s findings have important implications for better understanding the neurological basis for ASD and developing effective therapies for patients.

Crispr-cas9 biotechnology dna gene engineering and manipulation. Modern Innovative Healthcare. Crispr cas.

article

Developing novel genome editing tools

31 October 2022 | By Dr Stephen Jones (Vilnius University Life Sciences Center)

In this Q&A, Dr Stephen Jones from Vilnius University Life Sciences Center discusses his work on the recent developments in genome editing tools at the university.

Woman's eye with smart contact lens with digital and biometric implants to scan the ocular retina close up. Concept of future and technology for digital scans

news

3D map reveals DNA organisation within human retina cells

25 October 2022 | By Ria Kakkad (Drug Target Review)

Scientists shed light on how genetic architecture in human retina cells determine gene expression, tissue-specific function, and disease phenotype in blinding diseases.

Microglia are immune cells in the brain, 3d illustration

article

How neurons stimulate the brain’s microglia

25 October 2022 | By Drug Target Review

A new MIT study highlights ailing neurons may activate an inflammatory response from the brain’s microglia immune cells.

Mitochondria, Cross section view of a mitochondrion 3d illustration

news

New mitochondrial disease identified in identical twins

18 October 2022 | By Izzy Wood (Drug Target Review)

Unlike other mitochondrial diseases, a newly discovered form leads to hyperactive mitochondria, causing patients to have low body weight despite excessive food intake.

Power up your LNP and AAV sample prep with Unagi

webinar

Power up your LNP and AAV sample prep with Unagi

12 October 2022 | By Unchained Labs

Watch this on-demand webinar to see first-hand data results demonstrating the power and flexibility of Unagi for nucleic acids, LNPs and AAVs.

news

Novel Zika vaccine shows promise in animal models

12 October 2022 | By Victoria Rees (Drug Target Review)

A potential Zika virus vaccine, developed by deleting part of the Zika genome that codes for the viral shell, was effective and safe in mice.

news

Improved AAV could cross blood-brain barrier and deliver gene therapies to CNS

11 October 2022 | By Victoria Rees (Drug Target Review)

A newly developed AAV has shown promise at delivering gene therapies to the brain in mice and non-human primates.

Optometrist or optician get colour blindness tested for child boy, vision and eye care concept

news

Researchers develop NPHP5 gene therapy for rare ciliopathy

20 September 2022 | By Ria Kakkad (Drug Target Review)

The researchers found that augmenting NPHP5 gene rescues cilia defects in light-sensing cells derived from ciliopathy patients.

article

Next-generation CRISPR technologies for treating human diseases

15 September 2022 | By Dr Pushpanathan Muthuirulan (Harvard University)

Genome editing technologies could accelerate the translation of genetic advances into new therapeutics. Here, Dr Pushpanathan Muthuirulan, Research Associate at Harvard University, explores the potential of CRISPR to treat and cure genetic conditions.

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Genomics