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Hit-to-Lead

video

Video: Overview of the KingFisher^TM instruments

10 June 2020 | By Thermo Fisher Scientific

ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.

video

Video: Isolate Circulating tumor cells using the KingFisher

9 June 2020 | By Thermo Fisher Scientfic

New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.

whitepaper

ebook: How FBDD improves hit rates & delivers high-value targets

8 June 2020 | By NanoTemper Technologies

Learn how fragment-based drug discovery improves hit rates and delivers higher-value targets using various biophysical methods.

whitepaper

Guide: Five ways biophysical tools help brain studies

3 June 2020 | By NanoTemper Technologies

Learn why researchers turned to biophysical methods to expose the molecular mechanisms of neurodegenerative diseases.

whitepaper

ebook: How to start your own lab

26 May 2020 | By NanoTemper Technologies

Learn practical tips from eight Principal Investigators about how to start your own lab.

whitepaper

ebook: High-content analysis and infectious disease

12 May 2020 | By PerkinElmer

Learn how you could use high-content analysis for functional & phenotypic assays in your infectious disease research or drug discovery.

webinar

Establishing Alpha CETSA HT in primary screening

7 May 2020 | By PerkinElmer

High-throughput screening (HTS) cascades have evolved to ensure that high quality hits can be identified from large screening collections.

news

Three new assays to test COVID-19 antivirals developed

30 April 2020 | By Victoria Rees (Drug Target Review)

A series of three new assays to screen for drug compounds or proteins that combat the COVID-19 coronavirus has been developed.

news

Researchers identify lead compounds for treatment of telomere diseases

23 April 2020 | By Victoria Rees (Drug Target Review)

Researchers investigating telomere dieases such as dyskeratosis congenita have found lead compounds that reverse cellular ageing in mouse models of the condition.

news

Lead SARS-CoV-2 inhibitor compound identified by researchers to treat COVID-19

23 April 2020 | By Victoria Rees (Drug Target Review)

Researchers have found a lead compound which they say inhibits SARS-CoV-2 viral replication and demonstrates good pharmacokinetic activity in vivo.

tablets, capsules and a laboratory scientist in a white coat on a swirling blue background

news

Screening 10,000 compounds identifies six potential COVID-19 therapeutics

17 April 2020 | By Hannah Balfour (Drug Target Review)

High-throughput screening of thousands of compounds has revealed several candidates, including lead compound ebselen, with the potential for treating COVID-19.

news

Celltrion selects 14 lead monoclonal antibodies for COVID-19 treatment

16 April 2020 | By Victoria Rees (Drug Target Review)

After screening 300 antibodies, Celltrion has identified the 14 most powerful that could potentially combat the COVID-19 coronavirus.

video

Video: Increased reproducibility with KingFisher™ instruments

8 April 2020 | By Thermo Fisher Scientific

ESHG 2019 Conference Presentation: Using KingFisher™ to increase reproducibility in new applications using challenging samples.

whitepaper

Article: Efficient collaboration and reproducibility crisis

7 April 2020 | By Gilson

Advances in technology, such as the development of connected lab instruments, can integrate into workflows to help address reproducibility challenges.

news

Celltrion to select lead antibody candidates to fight COVID-19

6 April 2020 | By Victoria Rees (Drug Target Review)

Following the screening of antibodies, Celltrion will now identify the most potent out of 300 hits that work against the COVID-19 coronavirus best.

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Hit-to-Lead