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Immunology

HIV cell being attacked by silver nanoparticles

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Potent nanoparticle may help improve vaccines for HIV and other diseases

7 December 2021 | By Anna Begley (Drug Target Review)

The new nanoparticle adjuvant improved antibody production following vaccination against HIV, diphtheria and influenza in mouse models.

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“Overlooked” FAM72A gene shines light on antibody production

3 December 2021 | By Anna Begley (Drug Target Review)

Scientists used a new screen to identify FAM72A as a cause of mutagenesis that affects antibody development in COVID-19 and cancer.

Picture of vaccine with "OMICRON" written in background

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Everest Medicines and Providence to develop Omicron vaccine

1 December 2021 | By Anna Begley (Drug Target Review)

Everest Medicines and Providence Therapeutics have started working on a new version of COVID-19 vaccine specifically targeting the new Omicron variant.

Woman with arthritus holding hand highlighted in red

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Rheumatoid arthritis discovery may lead to novel inflammation blockers

24 November 2021 | By Anna Begley (Drug Target Review)

A new study links tumour necrosis factor seen in rheumatoid arthritis with T cell dysfunction, potentially leading to new therapies.

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Genetic study could influence the development of COVID-19 therapies

23 November 2021 | By Anna Begley (Drug Target Review)

The study is the first in-depth look at links between COVID-19 severity and gene expression in immune cells and may guide future therapies.

Woman holding stomach with intestine illustration highlighted

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Stress hormones linked to Crohn’s disease flare-ups

22 November 2021 | By Anna Begley (Drug Target Review)

Removing stress hormones in mouse models restored proper function to immune cells and epithelial cells, pointing to new Crohn's treatments.

Man with inflammatory bowel system holding his stomach highlighted in red

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CRISPR screen unveils enzyme target for inflammatory diseases

19 November 2021 | By Anna Begley (Drug Target Review)

Scientists used a CRISPR-based screen to find that inhibiting MTHFD2 reduces disease severity in inflammatory disease models.

Woman in hospital bed with oxygen mask on surrounded by doctors

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New molecule could complement antibiotics to treat pneumonia

16 November 2021 | By Anna Begley (Drug Target Review)

Scientists targeted a mouse's own cells using a synthetic molecule called EEZE, presenting a novel way to treat pneumonia.

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Replication proteins a potential new target for COVID-19 vaccines

12 November 2021 | By Anna Begley (Drug Target Review)

A new study claims that future COVID-19 vaccines should activate T cells to attack infected cells expressing replication proteins.

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Monoclonal antibodies prevent COVID-19 inflammation in macaques

2 November 2021 | By Anna Begley (Drug Target Review)

Neutralising monoclonal antibodies protected aged macaque monkeys from SARS-CoV-2 and reduced inflammation, including in cerebrospinal fluid, a new study has shown.

Capturing biological complexity to empower biomarker discovery

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Capturing biological complexity to empower biomarker discovery

27 October 2021 | By Takara Bio

Watch this free one-hour session to discover how refined cell atlases can provide comprehensive roadmaps for health and disease.

whitepaper

Whitepaper: Phenotypic and functional CAR-T cell characterisation

25 October 2021 | By Sartorius AG

This whitepaper overviews phenotypic and functional characterisation of CAR-T cells with advanced flow cytometry and live-cell analysis.

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$2.6 million granted to create pan-coronavirus vaccine

25 October 2021 | By Anna Begley (Drug Target Review)

The La Jolla Institute for Immunology and Brigham and Women's Hospital will collaborate to develop a pan-coronavirus vaccine.

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Novel strategy successfully suppresses HIV infection in mice

25 October 2021 | By Anna Begley (Drug Target Review)

A new method, called synapse for T-cell activation (synTac), can attack HIV-infected T cells and may be a new cure for HIV and other diseases.

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Scientists identify protein that prevents HSV-1 brain damage

20 October 2021 | By Anna Begley (Drug Target Review)

Mammalian target of rapamycin complex 2 (mTORC2) was found to prevent brain damage in mice infected with herpes simplex virus 1 (HSV-1).

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Immunology