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T-cell exhaustion may limit long-term immunity in COVID-19 patients
Researchers suggest patients who develop mild COVID-19 may not be able to fight reinfection very effectively because their CD8+ T cells show signs of exhaustion.
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Immunology
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Targeting PEG2 reverses age-related cognitive decline in mice
The discovery of an inflammatory pathway promoting brain ageing and cognitive decline could lead to new treatments for age-related conditions.
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ebook: The organoid culture handbook
This tissue-specific handbook brings you key publications, in-house protocols and troubleshooting recommendations for your organoid cell culture.
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New method for rapid development of vaccines for pre-clinical tests
Using synthetic chemistry, researchers have fused hydrophobic adjuvants with water-soluble proteins to create a new type of vaccine.
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Recovered COVID-19 patients may be protected, but they could still transmit the virus
According to a Public Health England study, prior SARS-CoV-2 infection provides 83 percent protection against reinfection but may not stop individuals spreading COVID-19.
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Novel nanobody combinations protect cells from SARS-CoV-2 in vitro
By combining nanobodies targeting different regions of the SARS-CoV-2 Spike protein, researchers were able to protect cells from infection.
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Nanoparticle vaccine could protect against multiple coronaviruses
A new protein-based nanoparticle vaccine protected mice against a variety of coronaviruses, researchers have shown.
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Immune cells discovered in lungs improve flu defence, study shows
A team has found immune cells in the lungs after infection from the flu, which protected mice against reinfection from a different strain.
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Webinar: Novel flow cytometry ACE-2 blocking assay
This webinar from Bio-Techne demonstrates how to use a novel in vitro flow cytometry-based assay to monitor SARS-CoV-2 binding to ACE-2.
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A single approach to creating effective cancer and autoimmune disease therapeutics
Dr H. Michael Shepard, CEO and CSO of Enosi Life Sciences, discusses the similarities between cancer and autoimmune diseases, highlighting how this knowledge could be used to enhance treatments.
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Exploration of autoimmune disease target tissues reveals novel drug targets
Researchers suggest that identifying new treatments for autoimmune diseases requires studying the immune system AND target tissues together.
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Analysis finds COVID-19 infection may provide protective immunity
A new analysis suggests SARS-CoV-2-specific antibodies remain relatively stable for eight months and Spike protein-specific memory B cells increase in number over time.
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Whitepaper: Virus vaccine research – accelerated workflows
Discover how workflows are being accelerated to speed up the vaccine research and development process while maintaining safety and immunogenicity.
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RNA sequencing provides insights into why every SARS-CoV-2 infection is different
Associate Professor Pandurangan Vijayanand from La Jolla Institute for Immunology discusses his study into the body’s immune response to SARS-CoV-2 and why this can vary.
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Biomarkers for predicting COVID-19 disease severity
Scientists have created a prognostic classification model which uses biomarkers to help predict an individual’s risk of developing severe COVID-19 symptoms.
