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Mapping the immune response to COVID-19
Researchers reveal that a broad range of immune cells react to COVID-19 and aid recovery, findings which could inform the development of a potential vaccine.
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Immunology
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Researchers work to create a COVID-19 viral epitope map
The team used data from SARS-CoV to identify possible viral epitopes that vaccines could include to stimulate an immune response.
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Increasing ion channel function in cancer T cells could be new immunotherapy
Researchers have found that there is less calmodulin binding to ion channels in the T cells from cancer patients, presenting a new immunotherapeutic target.
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Study reveals how immune system handles fungal and viral infections
Researchers have studied how the human body responds to viral infection when already infected by fungi, offering insights into the immune system.
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New T-cell discovery could lead to treatments for both bacterial infections and autoimmune conditions
A novel highly activated form of T cells could be suppressed to treat autoimmune conditions and activated in treating bacterial infections.
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Boosting natural killer cells in mice with eczema relieves condition
Researchers have found that using IL-15 to boost natural killer cell numbers in mice helps to combat eczema and could be a therapeutic strategy for patients.
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Researchers generate atlas of thymus to understand T-cell development
A new study has created an atlas of human thymus development, to reveal which genes are needed for the production of specific T cells.
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Free radicals from immune cells cause salt-sensitive hypertension
A new study has found that in salt-sensitive hypertension, immune cells gather and release free radicals, damaging the kidneys.
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Molecular ‘switch’ could help treat or reverse age-related diseases
A molecular 'switch' that controls the immune machinery responsible for chronic inflammation has been identified which could help treat or even reverse the development of age-related conditions like Alzheimer's, Parkinson's, cancer and diabetes.
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Immune system regulator shifts immune cell balance
Researchers have provided new insight into the role of cyclic AMP (cAMP) in regulating the immune response which may lead to new ways of treating diseases.
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Blocking IL-17 could provide new multiple sclerosis treatment strategy
Researchers have revealed that inhibiting IL-17 could prevent the effects of autoimmune diseases, including multiple sclerosis.
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Molecule of blood found to be effective against lupus
Scientists have found that a molecule present in our blood, called C4BP (β-), could be used in a therapeutic capacity for lupus as well as potentially other autoimmune disorders.
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Study identifies gene responsible for T follicular helper cell development
A loss-of-function mutation in the Prkd2 gene has been revealed as a driver of T follicular helper cell development which could be useful for vaccine design.
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Researchers discover how gut infections may produce chronic symptoms
A new study into why neurons in the gut die and how the immune system protects them could lead to better treatments for IBS that work by boosting polyamine production.
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Process that immune cells use to detect infections and cancers discovered
Researchers have discovered how gamma-delta T cells become activated which could lead to the development of new and improved immunotherapy treatments.