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HIV vaccine elicits antibodies in animals that neutralise dozens of HIV strains
NIH study results represent a major advance for structure-based HIV vaccine design...
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Immunology
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CRISPR approach could limit toxicity of CAR-T therapy in AML
New study uses CRISPR/Cas9 to make CD33 CAR T cells cancer-specific...
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Researchers use blood serum markers to develop lupus risk index
Researchers have developed an index that identifies the risk for lupus based on the presence and amount of IgG and IgM antibodies and levels of C1q...
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IL-25 molecule linked to nasal polyps
Study could lead to the development of new treatments for common sinus conditions...
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Gut microbiome can control anti-tumour immune function in liver
Scientists have found a connection between bacteria in the gut and antitumor immune responses in the liver...
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Immune processes offer insights into triple-negative breast cancer
Researchers have discovered the process that allows immune suppressor cells to develop, suggesting a potential new way to bolster immunotherapy treatment...
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Link between TB and Parkinson’s disease identified
The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...
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Macrophages support mammary stem cells via chemical signalling
An international team of scientists has discovered that one of the biggest hitters in the immune system, macrophages, provide a cradle for mammary stem cells...
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NDF identified as the missing factor in gene activation
Scientists find the missing factor in gene activation...
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Scientists screen molecules for new prostate cancer drugs
Cancer researchers have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers...
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Research identifies novel unconventional type of immune cell capable of fighting viral infections
Research led by the University of Birmingham has identified a novel unconventional type of immune cell capable of fighting viral infections.
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Taking the brakes off the immune system: modelling effects in non-clinical safety studies
This article focuses on how the immune system functions, the challenges that it presents to drug development and why there are such concerns around safety that need to be investigated in pre-clinical studies. Moreover, it covers the role of checkpoint inhibitors as an attractive target for cancer immunotherapy.
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New insights into the origins of mutations in cancer
Scientists use data from human cancers and C. elegans to understand mutational causes of cancer...
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Psoriasis treated with compound derived from immune cells
A compound may be effective against other autoimmune diseases, mouse study shows...
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Researchers uncover origin of virus-fighting plasma B cells
A group of researchers have discovered an important mechanism that governs how B cells are chosen to become plasma cells...
