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Macrophages support mammary stem cells via chemical signalling
An international team of scientists has discovered that one of the biggest hitters in the immune system, macrophages, provide a cradle for mammary stem cells...
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Immunology
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NDF identified as the missing factor in gene activation
Scientists find the missing factor in gene activation...
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Scientists screen molecules for new prostate cancer drugs
Cancer researchers have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers...
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Research identifies novel unconventional type of immune cell capable of fighting viral infections
Research led by the University of Birmingham has identified a novel unconventional type of immune cell capable of fighting viral infections.
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Taking the brakes off the immune system: modelling effects in non-clinical safety studies
This article focuses on how the immune system functions, the challenges that it presents to drug development and why there are such concerns around safety that need to be investigated in pre-clinical studies. Moreover, it covers the role of checkpoint inhibitors as an attractive target for cancer immunotherapy.
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New insights into the origins of mutations in cancer
Scientists use data from human cancers and C. elegans to understand mutational causes of cancer...
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Psoriasis treated with compound derived from immune cells
A compound may be effective against other autoimmune diseases, mouse study shows...
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Researchers uncover origin of virus-fighting plasma B cells
A group of researchers have discovered an important mechanism that governs how B cells are chosen to become plasma cells...
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Antimicrobial therapy can prevent sepsis in pneumonia patients
Research sheds light on the initial phase of infectious disease and potential for prevention of pneumococcal septicaemia...
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How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
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Macular degeneration linked to ageing immune cells
Older cells promote inflammation, abnormal blood vessel growth that can lead to blindness...
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Microscopic revelations point to new blood infection therapies
Study shows that immune cells actually cause dangerous blood vessel blockage, in their rush to contain deadly fungal sepsis...
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HIC1 protein may protect against intestinal disease
Scientists find molecular link between Vitamin A derivative and mouse intestinal health...
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Local environment plays key role in breast cancer progression
While studying the complex correlation between tissue stiffness and breast cancer development, researchers found that cancer cells tend to become more aggressive when the surrounding tissue stiffens...
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Lipid asymmetry plays key role in activating immune cells
Researchers have shown that by preventing loss of membrane asymmetry it's possible to control the immune response...
