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Two new genes linked to Alzheimer’s risk
Researchers have identified two genes that influence a person’s risk of developing Alzheimer’s disease.
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Immunology
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Hidden herpes virus may play key role in MS and other brain disorders
The ubiquitous human herpes virus 6 (HHV-6) may play a critical role in impeding the brain's ability to repair itself in diseases like multiple sclerosis.
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Quick test finds signs of sepsis in a single drop of blood
A new portable device can quickly find markers of deadly, unpredictable sepsis infection from a single drop of blood.
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Cancer Research UK sets out latest £20m grand challenges
Cancer Research UK has launched the second phase of its global Grand Challenge by announcing eight new questions – identified as some of the biggest barriers to making progress against cancer – and inviting the world’s top scientists to come together with new proposals to tackle them.
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New gene mutations found in white blood cells in rheumatoid arthritis patients
Finnish researchers have found that an accumulation of gene mutations, similar to those typically seen in the development of cancer, also occur in some patients with rheumatoid arthritis.
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Cells change type to help or hinder immunity
Scientists have discovered a mechanism that provides a possible new target for allergy treatments, which may bring hope for asthma sufferers.
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New mouse model to better kidney cancer treatment
Research in the field of kidney cancer, also called renal cancer, is vital, because many patients with this disease still cannot be cured today.
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Scientists jump hurdle in HIV vaccine design
Scientists at The Scripps Research Institute (TSRI) have made another important advance in HIV vaccine design.
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Faulty immune cells may play role in alopecia and baldness
The new study suggests that defects in Tregs could be responsible for alopecia areata, a common autoimmune disorder that causes hair loss, and could potentially play a role in other forms of baldness, including male pattern baldness
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Immune cells found to be derived from specialised progenitors
Dendritic cells are gatekeepers of immunity and crucial for the detection and initiation of immunity against pathogens and foreign substances. Up to now, dendritic cell subtypes were thought to develop from one common progenitor. New findings from a team of researchers show with single cell resolution that this important component…
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Scientists uncover mechanism allowing bacteria to survive the human immune system
Researchers have uncovered molecular details of how pathogenic bacteria fight back against the human immune response to infection.
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Specialised blood vessels enhance tumour-fighting immunotherapy
The successful combination of two therapies results in the growth of specialised vessels that deliver cancer-fighting immune cells to a tumour, potentially leading to more effective treatments and longer survival periods.
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Nimbus Therapeutics enters into strategic partnership with Charles River Laboratories to advance new therapeutic programs
Nimbus Therapeutics and Charles River Laboratories International, Inc. (NYSE: CRL) launched a multi-year strategic partnership to advance new programs spanning the disease areas of immunology, metabolic disorders and oncology from the discovery phase through to Investigational New Drug (IND) submission.
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Drug Target Review – Issue #1 2017
Included in this issue: Importance of building patient trust; Vaccines & Immunology; Oncology; Assays; Biomarkers; and Antibodies...
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£100 million for Cancer Research’s ‘grand challenge’ competition winners
Cancer Research UK announced that four international teams are the first recipients of its global £100m Grand Challenge competition, which aims to overcome the biggest challenges facing cancer researchers in a global effort to beat cancer sooner.