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Application note: Afucosylated mAb expression & antibody efficacy
Sino Biological’s “FucoFree” eukaryotic expression system provides high-yield and high-throughput afucosylated monoclonal antibody (mAb) production.
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Immunology
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CEPI awards $5.2m funding for Nipah virus vaccine research
A Boston University researcher has been granted funding for the development pre-clinical models to test potential Nipah virus vaccines.
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Novel Zika vaccine shows promise in animal models
A potential Zika virus vaccine, developed by deleting part of the Zika genome that codes for the viral shell, was effective and safe in mice.
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Scientists push for development of intranasal COVID-19 vaccines
The best protection from COVID-19 will come from intranasally-delivered vaccines, due to the effectiveness of mucosal IgA antibodies, say researchers from the University at Buffalo.
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Is an HIV vaccine on the horizon?
Researchers in the US have developed a potential HIV vaccine approach that aims to prompt the creation of broadly neutralising antibodies via mRNA.
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Advancing vaccines with extracellular vesicles
Dr Christopher Locher, Versatope Therapeutics, explains why bacterial extracellular vesicles are ideally suited for recombinant vaccines because target antigens can be expressed as fusion proteins and targeted to the lumen, membrane or surface of the vesicles. These nano-size vesicles represent a potentially safe and simple subunit vaccine delivery platform that…
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Application note: Flow cytometry platform
Compendium of iQue® advanced flow cytometry platform application posters: Antibody discovery and immuno-oncology.
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Whitepaper: Disease state primary cells bring verification and validation studies closer to real-world results
Discover how BioIVT’s portfolio of disease state LEUKOMAX® leukopaks and PBMCs can serve as representative starting materials for autologous cell therapy research.
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Application note: Studying Avi-tag protein interactions by SPR
Learn how R&D Systems™ Avi-tag biotinylated proteins can be used as an alternative to amine biotin coupling in surface plasmon resonance experiments.
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Advancing novel biotherapeutics based on synthetic biology
Researchers at Synlogic are clearing the path for a new class of medicine – biotherapeutics based on synthetic biology, called synthetic biotics, which are created by programming or engineering bacteria to metabolise or secrete well-validated targets of disease pathophysiology. In this article, Dr Caroline Kurtz, Chief Development Officer at Synlogic, discusses how synthetic…
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Whitepaper: Isolation of tumour infiltrating lymphocytes from dissociated tumour cells
Discover how BioIVT’s dissociated tumour cells (DTCs) can be used for tumour-infiltrating lymphocyte (TIL) cell therapy research.
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Case Study: Trust in your results — A flow cytometry case study
Trust in your results — Experience the benefits of iQue® advanced flow cytometry.
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Whitepaper: Detecting CAR-T cells using Fluorokines™
This article outlines the advantages of using R&D Systems™ fluorescent-labeled proteins to directly stain and detect CAR+ cells by flow cytometry.
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Application note: Hyperion+ imaging system
A powerful tool to study complex phenotypes and cellular interactions. Map spatial interactions twice as fast with this second-generation system.
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Application note: Quantifying T Cell response in 3D tumour spheroids
Application note: Quantifying T Cell response in 3D tumour spheroids using advanced flow cytometry workflows.
