news Experimental drug boosts immunotherapy efficacy for pancreatic cancer 4 November 2021 | By Anna Begley (Drug Target Review) An experimental drug enhanced the benefit of immunotherapy, reducing and in some cases eliminating pancreatic cancer in mice.
podcasts Episode 3 – Cell & gene therapy with Dr Sam Wadsworth, Ultragenyx Pharmaceutical & Dr Eric Ostertag, Poseida Therapeutics 1 November 2021 | By Drug Target Review Tune in to this podcast to learn about AAV vectors for gene therapy delivery and engineering CAR T cells against solid tumours.
news Raman spectroscopy used to determine immunotherapy effectiveness 28 October 2021 | By Anna Begley (Drug Target Review) Researchers used Raman spectroscopy to monitor immunotherapy response in mice, potentially improving cancer treatments in the future.
video Engineering better CAR T cells with Professor Ann Ager, Cardiff University 27 October 2021 | By Drug Target Review Watch this exclusive interview with Professor Ann Ager, Cardiff University, to discover how CAR T cells could be targeted against solid tumours.
news Medicenna’s MDNA11 a promising alternative to checkpoint inhibitors 19 October 2021 | By Anna Begley (Drug Target Review) Medicenna's IL-2 super-agonist, MDNA11, successfully induced antitumour cells in animal models, a pre-clinical study has revealed.
news Scientists uncover answer to colorectal cancer immunotherapy resistance 13 October 2021 | By Anna Begley (Drug Target Review) Boosting dendritic cells prevented immunotherapy resistance in mouse models, suggesting a new approach to colorectal cancer therapies.
news Antidepressants inhibit growth of pancreatic and colon cancers in mice 29 September 2021 | By Anna Begley (Drug Target Review) Scientists have discovered that approved antidepressant drugs cause immune cells to recognise and eliminate tumour cells in mouse models.
news “Ultrasensitive” HPV detection paves way for precision treatment 28 September 2021 | By Anna Begley (Drug Target Review) A new study sequenced tumour DNA for the “ultrasensitive” detection of HPV, further honing precision treatment of the illness.
news New AI method could aid in development of T cell-based cancer therapies 24 September 2021 | By Anna Begley (Drug Target Review) An artificial intelligence technique can identify which neoantigens are recognised by the immune system, possibly improving cancer prognosis and treatment.
news Club cell factors may reverse immune suppression in tumours 21 September 2021 | By Anna Begley (Drug Target Review) New research has revealed that club cells secret anti-immunosuppressive factors in tumours, potentially revolutionising cancer therapies.
news Controlling PTEN gene could combat paediatric rhabdomyosarcoma 20 September 2021 | By Anna Begley (Drug Target Review) The decreased expression of PTEN in mouse models was found to make rhabdomyosarcoma tumours more aggressive, highlighting new treatment approaches.
whitepaper Cell & Gene Therapy Advancements Whitepaper 16 September 2021 | By Drug Target Review Download this whitepaper to discover the latest research and developments in cell and gene therapies via exclusive articles and interviews.
news Novel tool can estimate number of T cells in cancer tumours 10 September 2021 | By Anna Begley (Drug Target Review) Researchers have developed a new method that can rapidly count the number of T cells in a tumour, helping to predict patient response to therapies.
news STING-activating drugs could customise cancer treatments 9 September 2021 | By Anna Begley (Drug Target Review) An imaging technique identified emerging drugs that activate the STING protein to alter metabolic pathway activity in cancer cells.
news Stem-like T cells could improve immunotherapy treatments 7 September 2021 | By Anna Begley (Drug Target Review) Targeting stem-like T cells within certain lymph nodes could improve the number of cancer patients that respond to immunotherapy treatments.