news
A new strategy to overcome tumour-induced immunosuppression
Researchers have found that blocking key enzymes could boost anti-cancer T cell responses and resistance to immunosuppression.
List view / Grid view
Immunotherapy
news
How T cells migrate from the tissue to the lymph nodes
Scientists have found that unconventional T cells migrate from tissue into the lymph nodes and influence immune responses there.
news
A modified TB vaccine could treat bladder cancer
An animal study has shown that a modified vaccine for tuberculosis could treat bladder cancer whilst minimising side effects.
news
Researchers develop a small molecule that makes immunotherapy available to all cancer patients
Scientists have identified and synthesised a small molecule that could be a more accessible and affective alternative to an antibody that treats a wide range of cancers.
news
Researchers halt the growth of multiple myeloma in mice
Scientists from Stanford University have been able to halt the growth of multiple myeloma and diffuse large B cell lymphoma in mice with custom molecule sBCMA-Fc V3.
news
Takeda enters agreement with F-star Therapeutics to license bispecific antibody
F-star Therapeutics has announced a licence agreement with Takeda for a novel next-generation immuno-oncology bispecific antibody.
news
Whole exome sequencing predicts whether cancer patients will respond to immunotherapy
Researchers have developed a two-step approach using whole exome sequencing to focus on genes and pathways that predict whether cancer patients will respond to immunotherapy.
news
Scientists map networks of disease-associated immune genes
The new immune gene networks have implications for developing immunotherapies and understanding autoimmune diseases.
news
How the innate immune system detects HIV-1
Researchers have found that the innate immune system requires two steps to defend against HIV-1, even when the virus is present in small amounts.
article
New immune targets to improve survival from sepsis
In a pre-clinical study, researchers from the US set out to develop a treatment for sepsis. Here, Daniel Morales-Mantilla, Dr Robin Parihar and Dr Katherine King, from Baylor College of Medicine, describe how they utilised haematopoietic stem and progenitor cell infusion to improve the survival of mice from sepsis.
news
Listeria-based booster improves vaccine’s protection against recurring cancer
New research has shown that using viral and bacterial vaccine approaches together is safe and far more effective at fighting the cancer than either approach by itself.
news
How tumours change immune cells to promote cancer growth
Researchers have found that soft-tissue sarcomas change the biology of immune cells surrounding tumours to promote tumour growth
news
New combination therapy exploits ‘natural killer’ cells to destroy head and neck tumours
Scientists have identified a new treatment combination that is highly effective at suppressing the growth of head and neck tumours.
news
Global team aims to bring next generation CAR T-cell therapies to children with solid tumours
The Mark Foundation for Cancer Research awards ~$12 million to Cancer Grand Challenges Team to develop new immunotherapies for childhood solid tumours.
news
Immunity boosting treatment enhances CAR T-cell therapy for blood cancers
A new study in mice has shown blood cancer treatment with protein interleukin-7 revs up T-cell immunotherapy.