news
Hydrogel used to revert cancer cells back to cancer stem cells
A new hydrogel has been shown to convert cancer cells to cancer stem cells within 24 hours, in six different human cancer cell line types.
List view / Grid view
In Vitro
news
Three common antiviral drugs effective against SARS-CoV-2 in vitro
A team has shown that tilorone, quinacrine and pyronaridine are effective at inhibiting the replication of SARS-CoV-2 in vitro.
news
Organ-on-a-chip model developed to aid sickle cell disease treatment
Researchers have developed a novel organ-on-a-chip model of sickle cell disease to improve personalised medicine.
news
Researchers develop model of early human embryo from skin cells
Scientists have created the first model of early human embryos by reprogramming fibroblasts into a blastocyst-like structures.
news
High-CBD cannabis extracts could provide COVID-19 treatment
Cannabidiol's (CBD) anti-inflammatory properties could be harnessed to treat or prevent COVID-19, according to a new study.
news
New inhibitor found to combat drug-resistant cancer cells
A team has developed a novel inhibitor that blocks a protein in cancer cells, making drug-resistant tumours respond to chemotherapy.
news
Researchers identify antibodies with potent effects against malaria
Six antibodies specific to the circumsporozoite protein of the malaria parasite have shown promise as therapeutic interventions, a study has shown.
article
NOX5: a novel target for sensitising melanoma to therapies
Vito Quaranta, professor of biochemistry and pharmacology, discusses how cancerous cells adopting novel mechanisms of energy production could be sensitised to existing therapies with a focus on melanoma.
news
Team modifies therapeutic molecule to improve stroke treatment
Researchers have shown that adding a polymer to glutamate-oxaloacetate transaminase means the molecule can treat stroke for up to six days in rats.
news
NAD depletion by IFN sensitises pancreatic cancer to NAMPT inhibition, study shows
High IFN signalling in pancreatic tumours are sensitive to NAMPT inhibitors which block a pathway in NAD synthesis, presenting a drug target.
news
Engineered peptide protects ferrets against SARS-CoV-2 transmission, study shows
A peptide administered to ferrets protected them from SARS-CoV-2 viral transmission when housed with infected ferrets.
news
New nanotherapy could potential treat Crohn’s disease in children
A novel nanotherapy can decrease intestinal inflammation and shrink lesions in rodent models of Crohn's disease, a study has shown.
news
New drug combination could combat Diffuse Intrinsic Pontine Glioma
The drug combination of difluoromethylornithine and AMXT 1501 has shown success against Diffuse Intrinsic Pontine Glioma in animal models.
news
Experimental vaccine against synthetic opioids shows success in mice
A new vaccine is effective at preventing opioid overdose from fentanyl and carfentanil in rodents, according to a new study.
news
Scientists reveal four discoveries about early SARS-CoV-2 infection
Researchers studying SARS-CoV-2 at the individual cellular level have made four major discoveries about early infection from the coronavirus.