news Ground-breaking small molecule attenuates neuroinflammation in mice 27 September 2021 | By Anna Begley (Drug Target Review) Limiting neuroinflammation was shown to be a promising approach to treat neurological diseases such as stroke and spinal cord injury in mice.
article Why there is a blockage in the biosample system 24 September 2021 | By Dr Robert Hewitt (Biosample Hub) Dr Robert Hewitt explores why a shift is required in the way that biosamples are sourced by the drug discovery industry, including smaller biotech companies.
news IL13Ra2 revealed as target against breast cancer-related brain metastasis 21 September 2021 | By Anna Begley (Drug Target Review) Interleukin 13 receptor alpha 2 was found in increased rates in cancer cells that metastasised to the brain and lungs, a new study has shown.
news Eczema may stem from poorly regulated sex hormones, study finds 20 September 2021 | By Anna Begley (Drug Target Review) A breaking discovery has revealed the gene HSD3B1 that regulates the production of sex hormones is linked to atopic dermatitis (AD).
news Novel technology could significantly advance genomics field 16 September 2021 | By Anna Begley (Drug Target Review) New technology system of drug-based markers for the selection or counter-selection of genes may advance genetic screening methods.
news Immune cells found co-operating to capture and “eat” bacteria 13 September 2021 | By Anna Begley (Drug Target Review) Researchers have identified a spider-like antibacterial mechanism by immune cells that could inspire Staphylococcus aureus treatments.
news Genetic defect in IBD patients linked to gut leakiness 6 September 2021 | By Anna Begley (Drug Target Review) A genetic defect in patients with inflammatory bowel disease (IBD) was found to affect how intestinal epithelial cells maintain a barrier.
news Innovative brain model provides patient-specific Alzheimer’s insights 3 September 2021 | By Anna Begley (Drug Target Review) Researchers have turned human stem cells into brain cells to create a new model that can predict cognitive decline rate on an individualised level.
news Immune cell changes detected in Waldenstrom macroglobulinemia (WM) 2 September 2021 | By Anna Begley (Drug Target Review) A new study has found mutations originating in blood progenitor cells, possibly leading to Waldenstrom macroglobulinemia (WM) therapies.
news DNA mechanism discovery may open up Huntington’s disease therapies 1 September 2021 | By Anna Begley (Drug Target Review) Scientists unveiled how a DNA repair protein may prevent Huntington’s disease, presenting a new target in future therapies.
news Novel model developed to resemble aberrant IPF lung epithelium 31 August 2021 | By Anna Begley (Drug Target Review) A new model that closely resembles aged lung epithelium in idiopathic pulmonary fibrosis has been developed, possibly leading to treatments.
news Detergent-like APOL3 protein shown to kill bacteria in human cells 27 August 2021 | By Anna Begley (Drug Target Review) Researchers have revealed that the protein APOL3 acts as a detergent in human cells, potentially leading to new antibacterial treatments.
article Getting “under the skin” of frontotemporal dementia 23 August 2021 | By Anna Begley (Drug Target Review) Researchers at the University of East Finland have been using skin cells to investigate pathological hallmarks in frontotemporal dementia patients.
news Existing drug may improve immune response to leukaemia treatment 18 August 2021 | By Anna Begley (Drug Target Review) Researchers identified the inhibitor JQ1 as a potential drug to improve immune response to CAR T-cell therapies in leukaemia patients.
news Quantifying method developed to improve neurodegeneration studies 18 August 2021 | By Anna Begley (Drug Target Review) Researchers have created a new method to quantify protein droplets involved in neurodegenerative diseases, enhancing the study of treatments.
