webinar
Integrated drug discovery panel – your questions answered!
28 September 2017 | By Charles River
During this peer panel discussion, team members from Charles River discussed their views and strategies on Drug Discovery...
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In Vivo
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Magnetic cellular ‘Legos’ for the regenerative medicine of the future
By incorporating magnetic nanoparticles in cells researchers have succeeded in creating cellular magnetic "Legos."...
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PerkinElmer launches new IVIS® Lumina™ S5 and Lumina X5 systems for high throughput in vivo imaging
Advanced 2D imaging and analysis help scientists rapidly trace anatomical and molecular aspects of diseases to advance drug discovery...
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Cell culture system could offer cancer breakthrough
A new cell culture system that provides a tool for preclinical cancer drug development and screening has been developed...
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Novel immunotherapy technology for prostate cancer
Scientists have described a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA...
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Bioprinted veins reveal new drug diffusion details
A scientific collaboration has developed vascularised 3-D bioprinted liver tissue constructs, providing more precise drug toxicity testing...
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Polyphor achieves first milestone from Wellcome for antibiotic development
Polyphor achieves first milestone from Wellcome Trust for the development of antibiotics against Gram-negative multi drug - resistant pathogens...
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Faulty immune cells may play role in alopecia and baldness
The new study suggests that defects in Tregs could be responsible for alopecia areata, a common autoimmune disorder that causes hair loss, and could potentially play a role in other forms of baldness, including male pattern baldness
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Collaborations in early drug discovery
The earliest phases of drug discovery used to be confined to research divisions of large pharmaceutical companies...
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PET/CT helps predict therapy effectiveness in paediatric brain tumours
Brain cancers are difficult to treat, and it can be hard to predict whether a therapy will be effective. When the patient is a child, it's even more important to predict the potential effectiveness of a drug before beginning treatment.
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Plasticell and Kings College London to collaborate in trials of blood platelet substitute
Over 10 million units of platelets are transfused worldwide each year in one of the most common procedures in clinical medicine. However, platelets derived from human donors can transmit infections and trigger serious immune reactions that eventually render the therapy ineffective (a condition known as alloimmune refractoriness). In addition, since…
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Tuberculosis: Researchers uncover how bacteria burst our cells
Scientists unveil the complex molecular structure that causes lethal infections by Mycobacterium tuberculosis (Mtb). Their findings might have implications for potential therapies against antibiotic-resistant tuberculosis.
webinar
Designing a Novel Cancer Drug: From Hit ID to Candidate
28 March 2017 | By Charles River
Discover how their multidisciplinary approach to hit ID, design and synthesis of novel chemical templates and development of targeted in vitro and in vivo assays resulted in the nomination of the first development candidate in just over two years...
webinar
Acute and inflammatory in vivo pain models
10 March 2017 | By Charles River
This webinar discusses our newly validated acute and inflammatory in vivo pain models, including information on how they were validated and how they can be used to test new pain treatment compounds, eventually leading to clinical translation...
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Positive results for Viking’s rare diseases in vivo study
Viking Therapeutics announced positive initial results from a proof-of-concept study of VK2809 in an in vivo model of glycogen storage disease Ia (GSD Ia).
